Active human ADAM12 protein fragment
| Name | Active human ADAM12 protein fragment |
|---|---|
| Supplier | Abcam |
| Catalog | ab174014 |
| Category | Protein |
| Prices | $372.00 |
| Sizes | 50 µg |
| Applications | SDS-PAGE FA |
| Species Reactivities | Human |
| Nature | Recombinant |
| Source | HEK 293 cells |
| Tag/Conjugation | His tag C-Terminus |
| Purity | > 98 % by SDS-PAGE. |
| Bioactivity | Measured by its ability to cleave IGFBP-3. The bioactivity was measured in 100 μL reaction mixture containing 20 µg/ml of ab174014 50 mM Tris, 10 mM CaCl 2 , 150 mM NaCl, pH 7.5. |
| Endotoxin | < 1.000 Eu/µg |
| SwissProt/Accession | O43184 |
| Gene | ADAM12 |
| Residue | 29 to 513 |
| Sequence | RGVSLWNQGRADEVVSASVGSGDLWIPVKSFDSKNHPEVLNIRLQRESKE LIINLERNEGLIASSFTETHYLQDGTDVSLARNYTGHCYYHGHVRGYSDS AVSLSTCSGLRGLIVFENESYVLEPMKSATNRYKLFPAKKLKSVRGSCGS HHNTPNLAAKNVFPPPSQTWARRHKRETLKATKYVELVIVADNREFQRQG KDLEKVKQRLIEIANHVDKFYRPLNIRIVLVGVEVWNDMDKCSVSQDPFT SLHEFLDWRKMKLLPRKSHDNAQLVSGVYFQGTTIGMAPIMSMCTADQSG GIVMDHSDNPLGAAVTLAHELGHNFGMNHDTLDRGCSCQMAVEKGGCIMN ASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRESFGGQKCGNRF VEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGTA CRDSSNSCDLPEFCTGASPHCPANVYLHDGHSCQD |
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Product images
Reduced SDS-PAGE analysis of ab174014, stained overnight with Coomassie Blue. DTT-reduced protein migrates as 28 kDa, 44 kDa and 68 kDa due to glycosylation corresponding to the propeptide, the mature form and the pro form respectively.