Gene Symbol | ADAM12 |
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Entrez Gene | 8038 |
Alt Symbol | ADAM12-OT1, CAR10, MCMP, MCMPMltna, MLTN, MLTNA |
Species | Human |
Gene Type | protein-coding |
Description | ADAM metallopeptidase domain 12 |
Other Description | disintegrin and metalloproteinase domain-containing protein 12|meltrin-alpha|metalloprotease-disintegrin 12 transmembrane |
Swissprots | Q6UWB0 Q5JRP0 O60470 Q5JRP1 Q6P9E3 O43184 |
Accessions | CBH19188 EAW49205 EAW49206 EAW49207 EAW49208 EAW49209 O43184 AF023476 AAC08702 AF023477 AAC08703 AK055628 AK127856 AK291629 BAF84318 AY358878 AAQ89237 BC060804 AAH60804 BX098286 CB960379 DA027173 DA863951 DR004947 HG975387 KF444157 AGX93290 T91975 NM_001288973 NP_001275902 NM_001288974 NP_001275903 NM_001288975 NP_001275904 NM_003474 NP_003465 NM_021641 NP_067673 |
Function | Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors (By similarity). {ECO:0000250}. |
Subcellular Location | Isoform 3: Secreted {ECO:0000305}. |
Tissue Specificity | Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. Not detected in brain, lung, liver, kidney or pancreas. |
Active human ADAM12 protein fragment - ab174014 from Abcam
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ADAM12 peptide - ab41205 from Abcam
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ADAM12 peptide - ab41207 from Abcam
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ADAM12 peptide - ab41204 from Abcam
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Human ADAM12 full length protein - ab53659 from Abcam
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Human ADAM12 peptide - ab45636 from Abcam
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ADAM12 Antibody Blocking Peptide - LS-E25784 from LifeSpan Bioscience
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ADAM12 Antibody Blocking Peptide - LS-E27740 from LifeSpan Bioscience
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ADAM12 Antibody Blocking Peptide - LS-E15203 from LifeSpan Bioscience
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ADAM12 Recombinant Protein - H00008038-P01 from Novus Biologicals
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Recombinant Human ADAM12 Protein - H00008038-Q01 from Novus Biologicals
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Recombinant Human ADAM12, CF - 4416-AD-020 from R&D Systems
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ADAM12 Protein (OPPA01859) - OPPA01859 from Aviva Systems Biology
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Human ADAM12 protein - orb80901 from Biorbyt
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ADAM12 Blocking Peptide - 33R-9503 from Fitzgerald
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ADAM12 Blocking Peptide - abx161006 from Abbexa
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ADAM12 Peptide - AC21-0613-P from Abcore
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ADAM12 Peptide - AC21-2551-P from Abcore
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ADAM12 / MLTN - H00008038-P01-10 from Acris Antibodies
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ADAM12 / MLTN - H00008038-P01-25 from Acris Antibodies
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ADAM12 / MLTN - H00008038-Q01-10 from Acris Antibodies
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ADAM12 / MLTN - H00008038-Q01-25 from Acris Antibodies
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A Disintegrin and Metalloproteinase Domain 12 S-Isoform, Human Recombinant - 228-10026-1 from RayBiotech
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Recombinant Human ADAM12 - 228-10026-2 from RayBiotech
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Recombinant Human ADAM12 - 228-10026-3 from RayBiotech
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