Name |
Recombinant Human TRAIL R2/TNFRSF10B Protein
|
Supplier |
Novus Biologicals
|
Catalog |
NBP2-35030
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Category |
Protein
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Prices |
$69.00, $169.00, $1,299.00
|
Sizes |
10 µg, 50 µg, 1 mg
|
Applications |
FA SDS-PAGE
|
Species Reactivities |
Human
|
Nature |
Recombinant
|
Source |
E. coli
|
Purity |
>95% pure by SDS-PAGE
|
Bioactivity |
TRAIL-R2 protein is fully biologically active when compared to standard. rHusTRAIL-R2 reduced the production of LPS-induced TNF by its ability to neutralize endogenous TRAIL in fresh human PBMC. In this assay, endogenous TRAIL is induced during a 24 hour exposure to LPS (10 ng/mL) but in the presence of rHusTRAIL-R2, TRAIL-induced TNF is suppressed.
|
Endotoxin |
Less than 1 EU/ug of endotoxin as determined by LAL method.
|
Gene |
TNFRSF10B
|
Sequence |
ESALITQQDL APQQRAAPQQ KRSSPSEGLC PPGHHISEDG RDCISCKYGQ DYSTHWNDLLFCLRCTRCDS GEVELSPCTT TRNTVCQCEE GTFREEDSPE MCRKCRTGCP RGMVKVGDCTPWSDIECVHK ES
|
Description |
A single, non-glycosylated biologically active polypeptide chain corresponding to 132 residues of TNFRSF10B. Source: E. coli Amino Acid Sequence: ESALITQQDL APQQRAAPQQ KRSSPSEGLC PPGHHISEDG RDCISCKYGQ DYSTHWNDLLFCLRCTRCDS GEVELSPCTT TRNTVCQCEE GTFREEDSPE MCRKCRTGCP RGMVKVGDCTPWSDIECVHK ES
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