TDP1, 1-298aa, Human, His tag, E.coli (Denatured)

Name TDP1, 1-298aa, Human, His tag, E.coli (Denatured)
Supplier ATGen
Catalog ATGP1950
Category Protein
Prices $80.00, $240.00, $720.00
Sizes 20 µg, 100 µg, 500 µg
Applications SDS-PAGE
Species Reactivities Human
Nature Recombinant
Tag/Conjugation His
Purity > 90% by SDS - PAGE
Gene TDP1
Description Tyrosyl-DNA phosphodiesterase 1, also known as TDP1, is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks
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