THOC7, 1-204aa, Human, His tag, E.coli

Name THOC7, 1-204aa, Human, His tag, E.coli
Supplier ATGen
Catalog ATGP2943
Category Protein
Prices $105.00, $320.00, $960.00
Sizes 10 µg, 50 µg, 250 µg
Applications SDS-PAGE
Species Reactivities Human
Nature Recombinant
Tag/Conjugation His
Purity > 90% by SDS - PAGE
Gene THOC7
Description THOC7 is required for efficient export of polyadenylated RNA. This protein acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway
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