| Name | Recombinant Human R-Spondin 4 Protein, CF |
|---|---|
| Supplier | R&D Systems |
| Catalog | 4575-RS/CF |
| Category | Protein |
| Prices | $329.00 |
| Sizes | 25 µg |
| Species Reactivities | Human |
| Nature | Recombinant |
| Source | Chinese Hamster Ovary cell line, CHO-derived Met1-Pro234 |
| Purity | >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
| Bioactivity | Measured by its ability to induce Topflash reporter activity in HEK293T human embryonic kidney cells. The ED 50 for this effect is 10‑60 ng/mL in the presence of 10 ng/mL Recombinant Mouse Wnt‑3a (Catalog # 1324-WN ). |
| Endotoxin | <0.01 EU per 1 μg of the protein by the LAL method. |
| SwissProt/Accession | Q2I0M5 |
| Gene | RSPO4 |
| Sequence | Ala19 |
| Supplier Page | Shop |
Wu C, Qiu S, Lu L, Zou J, Li WF, Wang O, Zhao H, Wang H, Tang J, Chen L, Xu T, Sun Z, Liao W, Luo G, Lu X. Nat Commun. 2014;5:3149.
Hao HX, Xie Y, Zhang Y, Charlat O, Oster E, Avello M, Lei H, Mickanin C, Liu D, Ruffner H, Mao X, Ma Q, Zamponi R, Bouwmeester T, Finan PM, Kirschner MW, Porter JA, Serluca FC, Cong F. Nature. 2012 Apr 29;485(7397):195-200.
Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J. Nature. 2012 Jul 26;487(7408):505-9.