Recombinant Human ADAMTS13 Protein, CF

• Supplier: R&D Systems
• Catalog: 4245-AD
• Category: Protein
• Prices: $329.00
• Sizes: 20 µg
• Species Reactivities: Human
• Nature: Recombinant
• Source: Chinese Hamster Ovary cell line, CHO-derived Gln34-Trp688, with a C-terminal 10-His tag
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Bioactivity: Measured by its ability to cleave the fluorogenic peptide substrate, FRETS-VWF73. The specific activity is >10 pmol/min/μg, as measured under the described conditions. See Activity Assay Protocol on www.RnDSystems.com.
• Endotoxin: <1.0 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: NP_620594
• Gene: ADAMTS13
• Sequence: No results obtained: Gln34 predicted

Product References

Probing ADAMTS13 substrate specificity using phage display. - Probing ADAMTS13 substrate specificity using phage display.

Desch KC, Kretz C, Yee A, Gildersleeve R, Metzger K, Agrawal N, Cheng J, Ginsburg D. PLoS One. 2015 Apr 7;10(4):e0122931.

Plasmin cleavage of von Willebrand factor as an emergency bypass for ADAMTS13 - Plasmin cleavage of von Willebrand factor as an emergency bypass for ADAMTS13

Tersteeg C, de Maat S, De Meyer SF, Smeets MW, Barendrecht AD, Roest M, Pasterkamp G, Fijnheer R, Vanhoorelbeke K, de Groot PG, Maas C. Circulation. 2014 Mar 25;129(12):1320-31.

The endogenous proteoglycan-degrading enzyme ADAMTS-4 promotes functional - The endogenous proteoglycan-degrading enzyme ADAMTS-4 promotes functional

Tauchi R, Imagama S, Natori T, Ohgomori T, Muramoto A, Shinjo R, Matsuyama Y, Ishiguro N, Kadomatsu K. J Neuroinflammation. 2012 Mar 15;9:53.

A novel calcium-binding site of von Willebrand factor A2 domain regulates its - A novel calcium-binding site of von Willebrand factor A2 domain regulates its

Zhou M, Dong X, Baldauf C, Chen H, Zhou Y, Springer TA, Luo X, Zhong C, Grater F, Ding J. Blood. 2011 Apr 28;117(17):4623-31.