ADAMTS13
| Gene Symbol | ADAMTS13 |
|---|---|
| Entrez Gene | 11093 |
| Alt Symbol | ADAM-TS13, ADAMTS-13, C9orf8, VWFCP, vWF-CP |
| Species | Human |
| Gene Type | protein-coding |
| Description | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| Other Description | A disintegrin and metalloproteinase with thrombospondin motifs 13|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13|vWF-cleaving protease|von Willebrand factor-cleaving protease |
| Swissprots | Q9UGQ1 Q96L37 Q710F6 Q9H0G3 Q711T8 Q6UY16 Q76LX8 |
| Accessions | AAS54901 AAS54902 AAS54903 AAS54904 ABD72606 ADD92168 CAI12850 CAI12851 CAI12852 EAW88083 EAW88084 EAW88085 EAW88086 EAW88087 EAW88088 Q76LX8 AB069698 BAB69487 AF414400 AAL11094 AF414401 AAL11095 AJ011374 CAB66157 AJ305314 CAC83682 AJ420810 CAD12729 AJ420811 CAD12730 AK124983 BAG54119 AK292439 BAF85128 AL136809 CAB66743 AV655072 AW197188 AY055376 AAL17652 AY358118 AAQ88485 BC034404 BC039251 BC103828 BC103829 BC103830 BC172369 AAI72369 DB069518 XM_011518174 XP_011516476 XM_011518175 XP_011516477 XM_011518176 XP_011516478 XM_011518177 XP_011516479 XM_011518178 XP_011516480 XM_011518179 XP_011516481 XM_011518180 XP_011516482 XM_011548750 XP_011547052 XM_011548751 XP_011547053 XM_011548752 XP_011547054 XM_011548753 XP_011547055 XM_011548754 XP_011547056 XM_011548755 XP_011547057 XM_011548756 XP_011547058 NM_139025 NP_620594 NM_139026 NP_620595 NM_139027 NP_620596 NR_024514 NM_139028 |
| Function | Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation. {ECO:0000269|PubMed:19880749}. |
| Subcellular Location | Secreted {ECO:0000269|PubMed:12791682}. Note=Secretion enhanced by O-fucosylation of TSP type-1 repeats. |
| Tissue Specificity | Plasma. Expressed primarily in liver. {ECO:0000269|PubMed:11574066}. |
ADAMTS13 peptide - ab41248 from Abcam
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ADAMTS13 peptide - ab41249 from Abcam
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ADAMTS13 peptide - ab41251 from Abcam
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Human ADAMTS13 full length protein - ab132357 from Abcam
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Human ADAMTS13 protein fragment - ab112399 from Abcam
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ADAMTS13 Antibody Blocking Peptide - LS-E8954 from LifeSpan Bioscience
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ADAMTS13 Partial Recombinant Protein - H00011093-Q01 from Novus Biologicals
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ADAMTS13 Recombinant Protein - H00011093-P01 from Novus Biologicals
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ADAMTS13-Antibody-Center-Blocking-Peptide - BP7438c from Abgent, a WuXi AppTec company
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Recombinant Human ADAMTS13, CF - 4245-AD-020 from R&D Systems
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Recombinant Human ADAMTS13 (Full Length), CF - 6156-AD-020 from R&D Systems
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ADAMTS13 - H00011093-P01-10 from Acris Antibodies
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ADAMTS13 - H00011093-P01-25 from Acris Antibodies
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ADAMTS13 - H00011093-Q01-10 from Acris Antibodies
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ADAMTS13 - H00011093-Q01-25 from Acris Antibodies
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Leucokinin-8 Peptide - 350242 from ABBIOTEC
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Recombinant Human ADAMTS13, His-tagged - ADAMTS13-136H from Creative Biomart
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Recombinant Human ADAMTS13, MYC/DDK-tagged - ADAMTS13-137H from Creative Biomart
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Recombinant Human ADAMTS13, His-tagged - ADAMTS13-820H from Creative Biomart
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Recombinant Von Willebrand Factor Cleaving Protease (vWFCP) - RPA950Hu01 from Uscn Life Science Inc.
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Recombinant Von Willebrand Factor Cleaving Protease (vWFCP) - RPA950Hu01 from Cloud-clone
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Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs - CSB-YP748481HU CSB-EP748481HU CSB-BP748481HU CSB-MP748481HU from Cusabio
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Recombinant Human ADAMTS13 Protein, CF - 4245-AD from R&D Systems
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Recombinant Human ADAMTS13 (Full Length) Protein, CF - 6156-AD from R&D Systems
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ADAMTS13 - MBS636953 from MyBioSource
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