Recombinant Human Kallikrein 14 Protein, CF

• Supplier: R&D Systems
• Catalog: 2626-SE
• Category: Protein
• Prices: $329.00
• Sizes: 10 µg
• Species Reactivities: Human
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived Gln19-Met248, with a C-terminal 10-His tag
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Bioactivity: Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC (Catalog # ES011 ). The specific activity is >3,000 pmol/min/µg, as measured under the described conditions. See Activity Assay Protocol on www.RnDSystems.com
• Endotoxin: <1.0 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: AAD50773
• Gene: KLK14
• Sequence: No results obtained: Gln19 predicted

Product References

Cross-linking of SPINK6 by transglutaminases protects from epidermal proteases. - Cross-linking of SPINK6 by transglutaminases protects from epidermal proteases.

Fischer J, Koblyakova Y, Latendorf T, Wu Z, Meyer-Hoffert U. J Invest Dermatol. 2013 May;133(5):1170-7.

Proteolytic activation cascade of the Netherton syndrome-defective protein, - Proteolytic activation cascade of the Netherton syndrome-defective protein,

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Isolation of SPINK6 in human skin: selective inhibitor of kallikrein-related - Isolation of SPINK6 in human skin: selective inhibitor of kallikrein-related

Meyer-Hoffert U, Wu Z, Kantyka T, Fischer J, Latendorf T, Hansmann B, Bartels J, He Y, Glaser R, Schroder JM. J Biol Chem. 2010 Oct 15;285(42):32174-81.

Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody - Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody

Sexton DJ, Chen T, Martik D, Kuzmic P, Kuang G, Chen J, Nixon AE, Zuraw BL, Forteza RM, Abraham WM, Wood CR. Biochem J. 2009 Aug 13;422(2):383-92.

Activation profiles and regulatory cascades of the human kallikrein-related - Activation profiles and regulatory cascades of the human kallikrein-related

Yoon H, Laxmikanthan G, Lee J, Blaber SI, Rodriguez A, Kogot JM, Scarisbrick IA, Blaber M. J Biol Chem. 2007 Nov 2;282(44):31852-64. Epub 2007 Sep 6.