Recombinant Mouse Fas/TNFRSF6/CD95 Fc Chimera Protein

Name Recombinant Mouse Fas/TNFRSF6/CD95 Fc Chimera Protein
Supplier R&D Systems
Catalog 435-FA
Category Protein
Prices $329.00
Sizes 50 µg
Species Reactivities Mouse
Nature Recombinant
Source Spodoptera frugiperda , Sf 21 (baculovirus)-derived Mouse FAS (Gly14 - Arg169) & (Arg35 - Arg169) Accession # P25446 DIEGRMD Human IgG 1 (Pro100 - Lys330) 6-His tag N-terminus C-terminus
Purity >97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Bioactivity Measured by its ability to inhibit Fas Ligand-induced apoptosis of Jurkat human acute T cell leukemia cells. The ED 50 for this effect is 0.03‑0.1 µg/mL in the presence of 20 ng/mL recombinant human Fas-ligand.
Endotoxin <0.1 EU per 1 μg of the protein by the LAL method.
SwissProt/Accession P25446
Gene Fas
Sequence Gly14 & Arg35
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Product References

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Tissue inhibitor of metalloproteinases-3 facilitates Fas-mediated neuronal cell - Tissue inhibitor of metalloproteinases-3 facilitates Fas-mediated neuronal cell

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Bheeshmachar G, Purushotaman D, Sade H, Gunasekharan V, Rangarajan A, Sarin A. J Immunol. 2006 Oct 15;177(8):5041-50.