Fas

Gene Symbol	Fas
Entrez Gene	14102
Alt Symbol	AI196731, APO1, APT1, CD95, TNFR6, Tnfrsf6, lpr
Species	Mouse
Gene Type	protein-coding
Description	Fas (TNF receptor superfamily member 6)
Other Description	FASLG receptor|Fas (TNF receptor superfamily member)|Fas antigen|apo-1 antigen|apoptosis-mediating surface antigen FAS|lymphoproliferation|tumor necrosis factor receptor superfamily member 6
Swissprots	Q9DCQ1 Q6GT31 P25446
Accessions	AAB25700 AAG02410 AAK27371 AAY51770 AAY51771 AAY51772 AAY51773 AAY51774 CAC00638 EDL41748 P25446 AK002590 BAB22211 AK086933 BAC39766 BC061160 AAH61160 BY348234 DQ846748 ABI24112 DQ846749 ABI24113 L15352 L15353 L25336 M83649 AAA37593 XM_011247141 XP_011245443 NM_001146708 NP_001140180 NM_007987 NP_032013
Function	Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity). {ECO:0000250}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Detected in various tissues including thymus, liver, lung, heart, and adult ovary.
Top Pathways	Apoptosis, Proteoglycans in cancer, Non-alcoholic fatty liver disease (NAFLD), p53 signaling pathway, TNF signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Recombinant Mouse Fas/TNFRSF6 Fc Chimera - 435-FA-050 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived

Recombinant Mouse Fas/TNFRSF6 Fc Chimera, CF - 435-FA-050/CF from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived

Mouse CD95 protein - orb83661 from Biorbyt Category Protein Prices $510.00, $748.00 Sizes 50 μg, 100 μg Source Human Species Mouse

Mouse FAS Protein - abx066478 from Abbexa Category Protein Source E.coli Species Mouse

Mouse FAS Protein - abx066480 from Abbexa Category Protein Source E.coli Species Mouse

CD95 / FAS - AR05247PU-S from Acris Antibodies Category Protein Prices $630.00 Sizes 25 µg Source Human Species Human

Factor Related Apoptosis (FAS), Mouse - 20-6085 from ARP American Research Products Category Protein Prices $419.00 Sizes 50 µg Source E.coli Species Mouse

Factor Related Apoptosis (FAS), Mouse - 20-6086 from ARP American Research Products Category Protein Prices $419.00 Sizes 50 µg Source E.coli Species Mouse

Recombinant Mouse Fas, His tagged - Fas-3268M from Creative Biomart Category Protein Source Human Cells Species Mouse

Recombinant Mouse Fas (TNF Receptor Superfamily Member 6) - Fas-1735M from Creative Biomart Category Protein Source Sf 21 Insect Cells .

Recombinant Factor Related Apoptosis (FAS) - RPA030Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Factor Related Apoptosis (FAS) - RPA030Mu02 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Mouse Tumor necrosis factor receptor superfamily member 6(Fas) - CSB-YP008433MO CSB-EP008433MO CSB-BP008433MO CSB-MP008433MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Recombinant Mouse Fas/TNFRSF6/CD95 Fc Chimera Protein - 435-FA from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Spodoptera frugiperda , Sf 21 (baculovirus)-derived Mouse FAS (Gly14 - Arg169) & (Arg35 - Arg169) Accession # P25446 DIEGRMD Human IgG 1 (Pro100 - Lys330) 6-His tag N-terminus C-terminus Species Mouse

Recombinant Mouse Fas/TNFRSF6/CD95 Fc Chimera Protein, CF - 435-FA/CF from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Spodoptera frugiperda , Sf 21 (baculovirus)-derived Mouse FAS (Gly14 - Arg169) & (Arg35 - Arg169) Accession # P25446 DIEGRMD Human IgG 1 (Pro100 - Lys330) 6-His tag N-terminus C-terminus Species Mouse

Fas/Apo1, Peptide - MBS843596 from MyBioSource Category Peptide Prices $165.00 Sizes 50 µg

Hsp27, Peptide - MBS843713 from MyBioSource Category Peptide Prices $165.00 Sizes 50 µg

Recombinant Lysophospholipase I (LYPLA1) - RPC575Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Factor Related Apoptosis (FAS), Recombinant Protein - MBS2010416 from MyBioSource Category Protein Prices $160.00, $320.00, $495.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Mouse

Factor Related Apoptosis (FAS), Recombinant Protein - MBS2009164 from MyBioSource Category Protein Prices $160.00, $320.00, $495.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Mouse

FAS Recombinant Protein (OPCD03081) - OPCD03081 from Aviva Systems Biology Category Protein Source E.coli Species Mouse

FAS Recombinant Protein (OPCD03085) - OPCD03085 from Aviva Systems Biology Category Protein Source E.coli Species Mouse

FAS / CD95 / APO-1 / TNFRSF6, Recombinant Protein - MBS2547202 from MyBioSource Category Protein Prices $475.00, $775.00 Sizes 50 µg, 100 µg Source Human Cells

Recombinant Mouse Fas,TNFRSF6,CD95 (C-6His) - AP76331 from Signalway Antibody Category Protein Prices $269.00, $479.00, $2,289.00, $3,209.00 Sizes 10 µg, 50 µg, 500 µg, 1 mg Source Human Cells Species Mouse

Recombinant Mouse Fas,TNFRSF6,CD95 (C-Fc) - AP76332 from Signalway Antibody Category Protein Prices $269.00, $479.00, $2,289.00, $3,209.00 Sizes 10 µg, 50 µg, 500 µg, 1 mg Source Human Cells Species Mouse

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