| Name | Recombinant Human IL-23 R Fc Chimera Protein, CF |
|---|---|
| Supplier | R&D Systems |
| Catalog | 1400-IR |
| Category | Protein |
| Prices | $339.00 |
| Sizes | 50 µg |
| Species Reactivities | Human |
| Nature | Recombinant |
| Source | Mouse myeloma cell line, NS0-derived Human IL-23 R (Gly24 - Asp353) Accession # Q5VWK5 IEGRMD Human IgG 1 (Pro100 - Lys330) N-terminus C-terminus |
| Purity | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain |
| Bioactivity | Measured by its ability to inhibit IL-23 induced IL-17 secretion by mouse splenocytes. The ED 50 for this effect is 0.008-0.04 µg/mL in the presence of 0.3 ng/mL of rhIL-23. |
| Endotoxin | <0.10 EU per 1 μg of the protein by the LAL method. |
| SwissProt/Accession | Q5VWK5 |
| Gene | IL23R |
| Sequence | Gly24 |
| Supplier Page | Shop |
Yu RY, Gallagher G. J Immunol. 2010 Dec 15;185(12):7302-8.
Vaknin-Dembinsky A, Balashov K, Weiner HL. J Immunol. 2006 Jun 15;176(12):7768-74.