IL23R

Gene Symbol	IL23R
Entrez Gene	149233
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	interleukin 23 receptor
Other Description	IL-23 receptor|interleukin-23 receptor
Swissprots	Q4VGP6 Q4VGP5 Q4VGP1 Q4VGP3 Q5VWK7 C9JGX4 Q96AS1 Q4VGP2 Q8IW84 Q8NFQ9 Q5VWK5 Q4VGP4
Accessions	BAJ13471 EAX06501 EAX06502 Q5VWK5 AF461422 AAM44229 AM990313 CAQ51232 AM990314 CAQ51233 AM990315 CAQ51234 AM990316 CAQ51235 AM990317 CAQ51236 AM990318 CAQ51237 AM990319 CAQ51238 AM990320 CAQ51239 AM990321 CAQ51240 AM990322 CAQ51241 AM990323 CAQ51242 AM990324 CAQ51243 AM990325 CAQ51244 AM990326 CAQ51245 AM990327 CAQ51246 AM990328 CAQ51247 AM990329 CAQ51248 AM990330 CAQ51249 AM990331 CAQ51250 AM990332 CAQ51251 AM990333 CAQ51252 AM990334 CAQ51253 AM990335 CAQ51254 AM990336 CAQ51255 AM990337 CAQ51256 AY937250 AAY18345 AY937251 AAY18346 AY937252 AAY18347 AY937253 AAY18348 AY937254 AAY18349 AY937255 AAY18350 BC016829 AAH16829 BC040720 AAH40720 BC142955 BC166698 AAI66698 FM212237 CAR79024 FM212238 CAR79025 FM212239 CAR79026 FM212240 CAR79027 FM212241 CAR79028 XM_005270516 XP_005270573 XM_011540789 XP_011539091 XM_011540790 XP_011539092 XM_011540791 XP_011539093 NM_144701 NP_653302
Function	Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. {ECO:0000269|PubMed:12023369}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:12023369}; Single-pass type I membrane protein {ECO:0000269|PubMed:12023369}.
Tissue Specificity	Expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells. {ECO:0000269|PubMed:12023369, ECO:0000269|PubMed:16372191}.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Inflammatory bowel disease (IBD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IL23 Receptor protein fragment - ab126013 from Abcam Category Protein Source E. coli Species Human

IL23R Antibody Blocking Peptide - LS-E4650 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IL-23 R Partial Recombinant Protein - H00149233-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

IL-23 R Recombinant Protein - H00149233-G01-10ug from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

IL23R-Antibody-C-term-Blocking-Peptide - BP17012b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human IL-23 R Fc Chimera, CF - 1400-IR-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human Interleukin-23 receptor protein - orb139187 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells Species Human

Cynomolgus Interleukin-23 receptor protein - orb139185 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells

Interleukin-23 receptor / IL23R - H00149233-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Interleukin-23 receptor / IL23R - H00149233-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human IL23R, Fc tagged - IL23R-8614H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human Il23R, HIgG1 Fc-tagged - Il23R-8616H from Creative Biomart Category Protein Source CHO cell Species Human

Recombinant Human Il23r, HIgG1 Fc-tagged - Il23r-8617H from Creative Biomart Category Protein Source CHO cell Species Human

Recombinant Human Il23R, MIgG2a Fc-tagged - Il23R-8615H from Creative Biomart Category Protein Source CHO cell Species Human

Recombinant Interleukin 23 Receptor (IL23R) - RPE765Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Interleukin 23 Receptor (IL23R) - RPE765Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Human IL23R / IL23 Receptor Protein (Fc Tag) - 13840-H02H-50 from Sino Biological Category Protein Prices $178.00, $298.00 Sizes 50 µg, 100 µg Source Human Cells Species Human

Recombinant Interleukin 23 Receptor (IL23R) - RPE765Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Interleukin-23 receptor(IL23R) - CSB-YP733162HU CSB-EP733162HU CSB-BP733162HU CSB-MP733162HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human IL-23 R Fc Chimera Protein, CF - 1400-IR from R&D Systems Category Protein Prices $339.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Human IL-23 R (Gly24 - Asp353) Accession # Q5VWK5 IEGRMD Human IgG 1 (Pro100 - Lys330) N-terminus C-terminus Species Human

IL-23 R Recombinant Protein Antigen - NBP2-47419PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Human IL-23 Recetor protein - orb334284 from Biorbyt Category Protein Prices $264.00, $451.00, $2,032.00, $2,882.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

HumanKine® IL-23, Human Recombinant Xeno-Free - GF424 from EMD Millipore Prices $306.00 Sizes 10 µg Source HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free. Species Human

IL23R Peptide, Human - M34GP07580H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human IL-23 Recetor protein - orb334285 from Biorbyt Category Protein Prices $264.00, $451.00, $2,032.00, $2,882.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

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