Recombinant Rat Fas/TNFRSF6/CD95 Fc Chimera Protein, CF

Name Recombinant Rat Fas/TNFRSF6/CD95 Fc Chimera Protein, CF
Supplier R&D Systems
Catalog 2159-FA
Category Protein
Prices $329.00
Sizes 50 µg
Species Reactivities Rat
Nature Recombinant
Source Mouse myeloma cell line, NS0-derived Rat Fas (Gln22 - Lys170) Accession # NP_631933 IEGRMD Human IgG 1 (Pro100 - Lys330) N-terminus C-terminus
Purity >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Bioactivity Measured by its ability to inhibit Fas Ligand-induced apoptosis of Jurkat human acute T cell leukemia cells. Cheng, J. et al . (1994) Science 263 :1759. The ED 50 for this effect is 0.05-0.25 µg/mL in the presence of 100 ng/mL recombinant rat Fas Ligand.
Endotoxin <0.10 EU per 1 μg of the protein by the LAL method.
SwissProt/Accession NP_631933
Gene Fas
Sequence No results obtained: Gln22 predicted
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Product References

c-Jun N-terminal kinases mediate Fas-induced neurite regeneration in PC12 cells. - c-Jun N-terminal kinases mediate Fas-induced neurite regeneration in PC12 cells.

Waetzig V, Loose K, Haeusgen W, Herdegen T. Biochem Pharmacol. 2008 Dec 1;76(11):1476-84.

Murine coronavirus-induced oligodendrocyte apoptosis is mediated through the - Murine coronavirus-induced oligodendrocyte apoptosis is mediated through the

Liu Y, Zhang X. Virology. 2007 Apr 10;360(2):364-75. Epub 2006 Dec 6.