Fas
| Gene Symbol | Fas |
|---|---|
| Entrez Gene | 246097 |
| Alt Symbol | Tnfrsf6 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | Fas cell surface death receptor |
| Other Description | CD95 antigen|FASLG receptor|Fas (TNF receptor superfamily, member 6)|Fas antigen (ATP1)|Fas receptor|Tumor necrosis factor receptor superfamily, member 6|apo-1 antigen|apoptosis-mediating surface antigen FAS|tumor necrosis factor receptor superfamily member 6 |
| Swissprots | Q63199 |
| Accessions | EDM13158 EDM13159 Q63199 AF104034 AAD20221 CB810875 D26113 BAA05109 FQ233018 NM_139194 NP_631933 |
| Function | Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity). {ECO:0000250}. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Top Pathways | Proteoglycans in cancer, Herpes simplex infection, TNF signaling pathway, Influenza A, Non-alcoholic fatty liver disease (NAFLD) |
Fas Ligand peptide - GTX22441 from GeneTex
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Recombinant Rat Fas/TNFRSF6 Fc Chimera, CF - 2159-FA-050 from R&D Systems
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Rat FAS Protein - abx066483 from Abbexa
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Rat FAS Protein - abx066481 from Abbexa
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Rat FAS Protein - abx066479 from Abbexa
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Factor Related Apoptosis (FAS), Rat - 20-6087 from ARP American Research Products
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Factor Related Apoptosis (FAS), Rat - 20-6088 from ARP American Research Products
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Factor Related Apoptosis (FAS), Rat - 20-6089 from ARP American Research Products
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Recombinant Rat Fas, His tagged - Fas-4096R from Creative Biomart
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Recombinant Rat Fas, Fc Chimera - Fas-823R from Creative Biomart
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Recombinant Rat Fas, Fc tagged - FAS-547R from Creative Biomart
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Rat FAS / CD95 / APO-1 / TNFRSF6 Protein (Fc Tag) - 80043-R02H-50 from Sino Biological
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Rat FAS / CD95 / APO-1 / TNFRSF6 Protein (His Tag) - 80043-R08H-50 from Sino Biological
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Recombinant Fatty Acid Synthase (FASN) - RPC470Ra01 from Cloud-clone
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Recombinant Rat Tumor necrosis factor receptor superfamily member 6(Fas) - CSB-YP737175RA CSB-EP737175RA CSB-BP737175RA CSB-MP737175RA from Cusabio
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Recombinant Rat Fas/TNFRSF6/CD95 Fc Chimera Protein, CF - 2159-FA from R&D Systems
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Recombinant Rat FAS / CD95 / APO-1 / TNFRSF6 Protein (His tag) - PKSR030383 from Elabscience
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Recombinant Rat FAS Protein - FAS-2273R from Creative Biomart
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Factor Related Apoptosis (FAS), Recombinant Protein - MBS2012200 from MyBioSource
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Factor Related Apoptosis (FAS), Recombinant Protein - MBS2011282 from MyBioSource
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Factor Related Apoptosis (FAS), Recombinant Protein - MBS2011830 from MyBioSource
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FAS Recombinant Protein (OPCD03087) - OPCD03087 from Aviva Systems Biology
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FAS Recombinant Protein (OPCD03088) - OPCD03088 from Aviva Systems Biology
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FAS Recombinant Protein (OPCD08009) - OPCD08009 from Aviva Systems Biology
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Rat FAS / CD95 / APO-1 / TNFRSF6 Protein (Fc Tag) - 80043-R02H from ABclonal
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