Recombinant Human Siglec-1 Protein, CF

Name Recombinant Human Siglec-1 Protein, CF
Supplier R&D Systems
Catalog 5197-SL
Category Protein
Prices $329.00
Sizes 50 µg
Species Reactivities Human
Nature Recombinant
Source Mouse myeloma cell line, NS0-derived Ser20-Gln1641, with a C-terminal 6-His tag
Purity >80%, by SDS-PAGE under reducing conditions and visualized by silver stain
Bioactivity Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. Kelm, S. et al . (1994) Current Biology 4 :965. The ED 50 for this effect is 0.6‑3 µg/mL.
Endotoxin <0.10 EU per 1 μg of the protein by the LAL method.
SwissProt/Accession Q9BZZ2
Gene SIGLEC1
Sequence Ser20
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Product References

Broad and direct interaction between TLR and Siglec families of pattern - Broad and direct interaction between TLR and Siglec families of pattern

Chen GY, Brown NK, Wu W, Khedri Z, Yu H, Chen X, van de Vlekkert D, D'Azzo A, Zheng P, Liu Y. Elife. 2014 Sep 3;3:e04066.

The role of Siglec-1 and SR-BI interaction in the phagocytosis of oxidized low - The role of Siglec-1 and SR-BI interaction in the phagocytosis of oxidized low

Xiong YS, Yu J, Li C, Zhu L, Wu LJ, Zhong RQ. PLoS One. 2013;8(3):e58831.

Siglecs facilitate HIV-1 infection of macrophages through adhesion with viral - Siglecs facilitate HIV-1 infection of macrophages through adhesion with viral

Zou Z, Chastain A, Moir S, Ford J, Trandem K, Martinelli E, Cicala C, Crocker P, Arthos J, Sun PD. PLoS One. 2011;6(9):e24559.