Recombinant Human Airway Trypsin-like Protease/HAT, CF

Name Recombinant Human Airway Trypsin-like Protease/HAT, CF
Supplier R&D Systems
Catalog 2695-SE
Category Protein
Prices $299.00
Sizes 10 µg
Species Reactivities Human
Nature Recombinant
Source Mouse myeloma cell line, NS0-derived Ala42-Ile418 with an N-terminal 6-His tag The protein was purified, activated and further purified.
Purity >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Bioactivity Measured by its ability to cleave the fluorogenic peptide substrate, t-butoxycarbonyl-Phe-Ser-Arg-7-amino-4-methyl coumarin (Boc-FSR-AMC). The specific activity is >50,000 pmol/min/µg, as measured under the described conditions. See Activity Assay Protocol on www.RnDSystems.com
Endotoxin <1.0 EU per 1 μg of the protein by the LAL method.
SwissProt/Accession O60235
Gene TMPRSS11D
Sequence Ile187 & His
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Product References

A peptide-based approach to evaluate the adaptability of influenza A virus to - A peptide-based approach to evaluate the adaptability of influenza A virus to

Straus MR, Whittaker GR. PLoS One. 2017 Mar 30;12(3):e0174827.

TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 - TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2

Heurich A, Hofmann-Winkler H, Gierer S, Liepold T, Jahn O, Pohlmann S. J Virol. 2014 Jan;88(2):1293-307.

Impact of host proteases on reovirus infection in the respiratory tract. - Impact of host proteases on reovirus infection in the respiratory tract.

Nygaard RM, Golden JW, Schiff LA. J Virol. 2012 Jan;86(2):1238-43.