TMPRSS11D

Gene Symbol	TMPRSS11D
Entrez Gene	9407
Alt Symbol	HAT
Species	Human
Gene Type	protein-coding
Description	transmembrane protease, serine 11D
Other Description	airway trypsin like protease|airway trypsin-like protease|transmembrane protease serine 11D
Swissprots	O60235 Q08AF6
Accessions	AAY40996 EAX05559 O60235 AB002134 BAA28691 AK094054 AK290289 BAF82978 AK296853 BAG59419 AL603214 BC033295 BC125195 AAI25196 BC125196 AAI25197 XM_005265710 XP_005265767 NM_004262 NP_004253
Function	May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Plays a role in the proteolytic processing of ACE2. Proteolytically cleaves and activates the human coronavirus 229E (HCoV-229E) spike glycoprotein which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. {ECO:0000269|PubMed:23536651, ECO:0000269|PubMed:24227843}.
Subcellular Location	Cell membrane; Single-pass type II membrane protein. Note=Activated by cleavage and secreted.
Tissue Specificity	Located in the cells of the submucosal serous glands of the bronchi and trachea.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TMPRSS11D full length protein - ab160473 from Abcam Category Protein Source Wheat germ Species Human

TMPRSS11D / HAT Antibody Blocking Peptide - LS-E16921 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TMPRSS11D / HAT Antibody Blocking Peptide - LS-E16922 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TMPRSS11D / HAT Antibody Blocking Peptide - LS-E27106 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Airway Trypsin-like Protease/HAT/TMPRSS11D Protein - H00009407-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TMPRSS11D blocking peptide - GTX88336-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Recombinant Human Airway Trypsin-like Protease/HAT, CF - 2695-SE-010 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Ala42-Ile418 with an N-terminal 6-His tag

Goat anti TMPRSS11D antibody Immunizing peptide - orb59593 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

TMPRSS11D Blocking Peptide - 33R-3987 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TMPRSS11D Blocking Peptide - 33R-8213 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TMPRSS11D Peptide - AC21-1928-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

TMPRSS11D - H00009407-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TMPRSS11D - H00009407-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TMPRSS11D Peptide - 42-101P from ProSci Category Peptide

TMPRSS11D fusion protein - ag17841 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

TMPRSS11D fusion protein - ag19061 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human TMPRSS11D, His-tagged - TMPRSS11D-22H from Creative Biomart Category Protein Source HEK293 Species Human

Recombinant Human TMPRSS11D, His-tagged - TMPRSS11D-996H from Creative Biomart Category Protein Source NSO Cells Species Human

Recombinant Human Transmembrane protease serine 11D(TMPRSS11D) - CSB-YP023918HU CSB-EP023918HU CSB-BP023918HU CSB-MP023918HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Airway Trypsin-like Protease/HAT, CF - 2695-SE from R&D Systems Category Protein Prices $299.00 Sizes 10 µg Source Mouse myeloma cell line, NS0-derived Ala42-Ile418 with an N-terminal 6-His tag The protein was purified, activated and further purified. Species Human

TMPRSS11D/HAT, Peptide - MBS425138 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

Airway Trypsin-like Protease/HAT/TMPRSS11D Recombinant Protein Antigen - NBP2-49065PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

HAT-Antibody-Center-Blocking-Peptide - BP6510c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TMPRSS11D-Blocking-Peptide-N-Term - BP21729a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TMPRSS11D Peptide, Human - M34GP16311H from Creative Peptides Category Peptide Source Synthetic. Species Human

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