Recombinant Human IL-15 R alpha Fc Chimera (HEK293), CF
| Name | Recombinant Human IL-15 R alpha Fc Chimera (HEK293), CF |
|---|---|
| Supplier | R&D Systems |
| Catalog | 7194-IR |
| Category | Protein |
| Prices | $329.00 |
| Sizes | 50 µg |
| Species Reactivities | Human |
| Nature | Recombinant |
| Source | Human embryonic kidney cell, HEK293-derived Human IL-15 R alpha (Met1 - Thr205) Accession # Q13261 IEGRMD Human IgG 1 (Pro100 - Lys330) N-terminus C-terminus |
| Purity | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain |
| Bioactivity | Measured by its ability to block human IL-15-induced proliferation of CTLL‑2 mouse cytotoxic T cells. Ruchatz, H. et al . (1998) J. Immunol. 160 :5654. The ED 50 for this effect is 2-10 ng/mL. |
| Endotoxin | <0.01 EU per 1 μg of the protein by the LAL method. |
| SwissProt/Accession | Q13261 |
| Gene | IL15RA |
| Sequence | Ile31 |
| Supplier Page | Shop |
Product images
Recombinant Human CTLA-4 Fc Chimera (Catalog # 325-CT/CF) inhibits IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells. The ED 50 for this effect is 0.1-0.4 μg/mL when stimulated with 1 μg/mL Recombinant Human B7-1 Fc Chimera (Catalog # 140-B1 ) in the presence of PHA.
1 μg/lane of Recombinant Human CTLA-4 Fc Chimera was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing single bands at 51 kDa and 94 kDa, respectively.
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