Recombinant Mouse Siglec-1 Fc Chimera Protein, CF

Name Recombinant Mouse Siglec-1 Fc Chimera Protein, CF
Supplier R&D Systems
Catalog 5610-SL
Category Protein
Prices $329.00
Sizes 50 µg
Species Reactivities Mouse
Nature Recombinant
Source Mouse myeloma cell line, NS0-derived Mouse Siglec-1 (Thr20 - Arg1639) Accession # CAM18034 IEGRMDP Mouse IgG 2a (Glu98 - Lys330) N-terminus C-terminus
Purity >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Bioactivity Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. Kelm, S. et al . (1994) Current Biology 4 :965. The ED 50 for this effect is 0.6-3 μg/mL.
Endotoxin <0.01 EU per 1 μg of the protein by the LAL method.
SwissProt/Accession CAM18034
Gene SIGLEC1
Sequence Thr20
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Product References

Broad and direct interaction between TLR and Siglec families of pattern - Broad and direct interaction between TLR and Siglec families of pattern

Chen GY, Brown NK, Wu W, Khedri Z, Yu H, Chen X, van de Vlekkert D, D'Azzo A, Zheng P, Liu Y. Elife. 2014 Sep 3;3:e04066.

The role of Siglec-1 and SR-BI interaction in the phagocytosis of oxidized low - The role of Siglec-1 and SR-BI interaction in the phagocytosis of oxidized low

Xiong YS, Yu J, Li C, Zhu L, Wu LJ, Zhong RQ. PLoS One. 2013;8(3):e58831.