Western blot analysis of extracts from NIH/3T3 cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® IGF-I Receptor β siRNA I (Mouse Specific) (+), or SignalSilence ® IGF-I Receptor β siRNA II (Mouse Specific) #12595 (+), using IGF-I Receptor β (D23H3) XP ® Rabbit mAb #9750 (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). The IGF-I Receptor β (D23H3) XP ® Rabbit mAb confirms silencing of IGF-I receptor β expression, while the β-Actin (D6A8) Rabbit mAb is used as a loading control.