Gene Symbol | GALP |
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Entrez Gene | 85569 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | galanin-like peptide |
Other Description | alarin|gal-like peptide |
Swissprots | Q9UBC7 A1KXL3 |
Accessions | EAW72431 Q9UBC7 AF188492 AAF19724 AF188493 AAF19725 AY329637 AAQ99038 BC141468 AAI41469 BC148722 AAI48723 NM_001145546 NP_001139018 NM_033106 NP_149097 |
Function | Isoform 1: Hypothalamic neuropeptide which binds to the G-protein-coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion. |
Subcellular Location | Secreted. |
Tissue Specificity | Isoform 2 is found in ganglia of ganglioneuroma and ganglioneuroblastoma, as well as in differentiated tumor cells of neuroblastoma tissues. Not found in undifferentiated neuroblasts. Isoform 2 is found in the skin, in pericytes covering microvascular arterioles and venules on their abluminal surfaces. In larger vessels, isoform 2 is expressed in layers of smooth muscle cells. Isoform 2 is not detected in endothelial cells. |
GALP CRISPR/Cas9 KO Plasmid (h) - sc-413793 from Santa Cruz Biotechnology
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GALP HDR Plasmid (h) - sc-413793-HDR from Santa Cruz Biotechnology
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GALP Double Nickase Plasmid (h) - sc-413793-NIC from Santa Cruz Biotechnology
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GALP Double Nickase Plasmid (h2) - sc-413793-NIC-2 from Santa Cruz Biotechnology
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GALP CRISPR Activation Plasmid (h) - sc-413793-ACT from Santa Cruz Biotechnology
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GALP CRISPR Activation Plasmid (h2) - sc-413793-ACT-2 from Santa Cruz Biotechnology
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GALP Lentiviral Activation Particles (h) - sc-413793-LAC from Santa Cruz Biotechnology
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GALP Lentiviral Activation Particles (h2) - sc-413793-LAC-2 from Santa Cruz Biotechnology
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GALP siRNA (h) - sc-97912 from Santa Cruz Biotechnology
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GALP shRNA Plasmid (h) - sc-97912-SH from Santa Cruz Biotechnology
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GALP shRNA (h) Lentiviral Particles - sc-97912-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN9120 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9120 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12198 from Sigma-Aldrich
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GALP siRNA (Human) - CRJ3841 from Cohesion Biosciences
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GALP - MBS8229918 from MyBioSource
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shRNA set against Human GALP (NM_033106.3) - SHH299173 from Creative biogene
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Human GALP siRNA - orb274342 from Biorbyt
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GALP shRNA Plasmid (Human) - CHJ3841 from Cohesion Biosciences
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GALP miRNA 3'UTR clone - MiUTR4H-TG11274 from Creative biogene
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