| Gene Symbol |
Scarb2
|
| Entrez Gene |
12492
|
| Alt Symbol |
9330185J12Rik, Cd36l2, LGP85, LIMP-2, MLGP85
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
scavenger receptor class B, member 2
|
| Other Description |
85 kDa lysosomal membrane sialoglycoprotein|CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2|LIMP II|lysosome membrane protein 2|lysosome membrane protein II
|
| Swissprots |
Q3UNF8 O35114
|
| Accessions |
EDL05248 O35114 AB008553 BAA23372 AK011123 BAB27416 AK032136 AK034388 AK036863 AK083038 BAC38740 AK144235 BAE25789 AK149102 AK170555 BAE41878 AK185315 AK195264 AK209796 AK210469 AK215249 AK215493 AK215612 AK219447 BC029073 AAH29073 NM_007644 NP_031670
|
| Function |
Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting. {ECO:0000269|PubMed:18022370, ECO:0000269|PubMed:24162852}.
|
| Subcellular Location |
Lysosome membrane {ECO:0000269|PubMed:24162852, ECO:0000269|PubMed:9399579}; Multi- pass membrane protein {ECO:0000269|PubMed:24162852, ECO:0000269|PubMed:9399579}.
|
| Tissue Specificity |
Detected in the extracts of brain, heart, lung, liver and kidney.
|
| Top Pathways |
Lysosome
|