Gene Symbol | Scarb2 |
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Entrez Gene | 12492 |
Alt Symbol | 9330185J12Rik, Cd36l2, LGP85, LIMP-2, MLGP85 |
Species | Mouse |
Gene Type | protein-coding |
Description | scavenger receptor class B, member 2 |
Other Description | 85 kDa lysosomal membrane sialoglycoprotein|CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2|LIMP II|lysosome membrane protein 2|lysosome membrane protein II |
Swissprots | Q3UNF8 O35114 |
Accessions | EDL05248 O35114 AB008553 BAA23372 AK011123 BAB27416 AK032136 AK034388 AK036863 AK083038 BAC38740 AK144235 BAE25789 AK149102 AK170555 BAE41878 AK185315 AK195264 AK209796 AK210469 AK215249 AK215493 AK215612 AK219447 BC029073 AAH29073 NM_007644 NP_031670 |
Function | Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting. {ECO:0000269|PubMed:18022370, ECO:0000269|PubMed:24162852}. |
Subcellular Location | Lysosome membrane {ECO:0000269|PubMed:24162852, ECO:0000269|PubMed:9399579}; Multi- pass membrane protein {ECO:0000269|PubMed:24162852, ECO:0000269|PubMed:9399579}. |
Tissue Specificity | Detected in the extracts of brain, heart, lung, liver and kidney. |
Top Pathways | Lysosome |
LIMP II CRISPR/Cas9 KO Plasmid (m) - sc-419546 from Santa Cruz Biotechnology
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LIMP II HDR Plasmid (m) - sc-419546-HDR from Santa Cruz Biotechnology
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LIMP II Double Nickase Plasmid (m) - sc-419546-NIC from Santa Cruz Biotechnology
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LIMP II Double Nickase Plasmid (m2) - sc-419546-NIC-2 from Santa Cruz Biotechnology
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LIMP II CRISPR Activation Plasmid (m) - sc-419546-ACT from Santa Cruz Biotechnology
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LIMP II CRISPR Activation Plasmid (m2) - sc-419546-ACT-2 from Santa Cruz Biotechnology
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LIMP II Lentiviral Activation Particles (m) - sc-419546-LAC from Santa Cruz Biotechnology
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LIMP II Lentiviral Activation Particles (m2) - sc-419546-LAC-2 from Santa Cruz Biotechnology
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LIMP II siRNA (m) - sc-41547 from Santa Cruz Biotechnology
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LIMP II shRNA Plasmid (m) - sc-41547-SH from Santa Cruz Biotechnology
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LIMP II shRNA (m) Lentiviral Particles - sc-41547-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU023991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN40749 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND40749 from Sigma-Aldrich
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SCARB2 siRNA (Mouse) - CRM0585 from Cohesion Biosciences
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SCARB2 - MBS8217599 from MyBioSource
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shRNA set against Mouse SCARB2 (NM_007644.3) - SHH402424 from Creative biogene
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shRNA set against Mouse Scarb2(NM_007644.3) - SHR207192 from Creative biogene
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SCARB2 shRNA Plasmid (Mouse) - CHM0585 from Cohesion Biosciences
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SCARB2 miRNA 3'UTR clone - MiUTR1M-10428 from Creative biogene
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