| Gene Symbol |
HIST1H2BH
|
| Entrez Gene |
8345
|
| Alt Symbol |
H2B/j, H2BFJ
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
histone cluster 1, H2bh
|
| Other Description |
H2B histone family, member J|histone 1, H2bh|histone H2B type 1-H|histone H2B.j
|
| Swissprots |
B2R541 Q4VB74 Q93079
|
| Accessions |
AAN06691 CAB02543 EAW55552 Q93079 AK312052 BAG34988 BC096116 AAH96116 BC096117 AAH96117 BC096118 AAH96118 BC096119 AAH96119 NM_003524 NP_003515
|
| Function |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
|
| Subcellular Location |
Nucleus. Chromosome.
|
| Top Pathways |
Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism
|