Gene Symbol | HIST1H2BH |
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Entrez Gene | 8345 |
Alt Symbol | H2B/j, H2BFJ |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H2bh |
Other Description | H2B histone family, member J|histone 1, H2bh|histone H2B type 1-H|histone H2B.j |
Swissprots | B2R541 Q4VB74 Q93079 |
Accessions | AAN06691 CAB02543 EAW55552 Q93079 AK312052 BAG34988 BC096116 AAH96116 BC096117 AAH96117 BC096118 AAH96118 BC096119 AAH96119 NM_003524 NP_003515 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism |
Histone cluster 1 H2BH CRISPR/Cas9 KO Plasmid (h) - sc-418574 from Santa Cruz Biotechnology
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Histone cluster 1 H2BH HDR Plasmid (h) - sc-418574-HDR from Santa Cruz Biotechnology
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Histone cluster 1 H2BH Double Nickase Plasmid (h) - sc-418574-NIC from Santa Cruz Biotechnology
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Histone cluster 1 H2BH Double Nickase Plasmid (h2) - sc-418574-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BH CRISPR Activation Plasmid (h) - sc-418574-ACT from Santa Cruz Biotechnology
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Histone cluster 1 H2BH CRISPR Activation Plasmid (h2) - sc-418574-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BH Lentiviral Activation Particles (h) - sc-418574-LAC from Santa Cruz Biotechnology
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Histone cluster 1 H2BH Lentiviral Activation Particles (h2) - sc-418574-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BH siRNA (h) - sc-105478 from Santa Cruz Biotechnology
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Histone cluster 1 H2BH shRNA Plasmid (h) - sc-105478-SH from Santa Cruz Biotechnology
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Histone cluster 1 H2BH shRNA (h) Lentiviral Particles - sc-105478-V from Santa Cruz Biotechnology
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HIST1H2BH RNAi - H00008345-R01 from Novus Biologicals
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MISSION® esiRNA - EHU112161 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10075 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10075 from Sigma-Aldrich
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HIST1H2BH siRNA (Human) - CRH5465 from Cohesion Biosciences
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HIST1H2BH - MBS8224986 from MyBioSource
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shRNA set against Human HIST1H2BH (NM_003524.2) - SHH312609 from Creative biogene
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shRNA set against Human HIST1H2BH(NM_003524.2) - SHH122447 from Creative biogene
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HIST1H2BH shRNA Plasmid (Human) - CHH5465 from Cohesion Biosciences
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HIST1H2BH miRNA 3'UTR clone - MiUTR1H-04536 from Creative biogene
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