| Gene Symbol |
NEURL1B
|
| Entrez Gene |
54492
|
| Alt Symbol |
NEURL3, hNeur2, neur2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
neuralized E3 ubiquitin protein ligase 1B
|
| Other Description |
E3 ubiquitin-protein ligase NEURL1B|E3 ubiquitin-protein ligase NEURL3|neuralized 2 alternative protein|neuralized homolog 1B|neuralized-2|neuralized-like protein 1B|neuralized-like protein 3
|
| Swissprots |
C9DQJ6 C9DQJ7 C9DQJ5 A8MQ27
|
| Accessions |
A8MQ27 AK026748 AK091605 AK096661 AK126311 CN267889 GQ414757 ACV53563 GQ414758 ACV53564 GQ414759 ACV53565 HY104395 XM_011534571 XP_011532873 NR_015355 NM_001142651 NP_001136123 NM_001308177 NP_001295106 NM_001308178 NP_001295107
|
| Function |
E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands. {ECO:0000269|PubMed:19723503}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:19723503}.
|
| Tissue Specificity |
Highest expression in brain, prostate and small intestine. In the brain the levels are higher in fetal than in adult stage. In the adult brain the highest levels are detected in the olfactory system, cerebellar cortex, optic nerve and the frontal lobe. {ECO:0000269|PubMed:19723503}.
|