NEURL1B

Gene Symbol NEURL1B
Entrez Gene 54492
Alt Symbol NEURL3, hNeur2, neur2
Species Human
Gene Type protein-coding
Description neuralized E3 ubiquitin protein ligase 1B
Other Description E3 ubiquitin-protein ligase NEURL1B|E3 ubiquitin-protein ligase NEURL3|neuralized 2 alternative protein|neuralized homolog 1B|neuralized-2|neuralized-like protein 1B|neuralized-like protein 3
Swissprots C9DQJ6 C9DQJ7 C9DQJ5 A8MQ27
Accessions A8MQ27 AK026748 AK091605 AK096661 AK126311 CN267889 GQ414757 ACV53563 GQ414758 ACV53564 GQ414759 ACV53565 HY104395 XM_011534571 XP_011532873 NR_015355 NM_001142651 NP_001136123 NM_001308177 NP_001295106 NM_001308178 NP_001295107
Function E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands. {ECO:0000269|PubMed:19723503}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:19723503}.
Tissue Specificity Highest expression in brain, prostate and small intestine. In the brain the levels are higher in fetal than in adult stage. In the adult brain the highest levels are detected in the olfactory system, cerebellar cortex, optic nerve and the frontal lobe. {ECO:0000269|PubMed:19723503}.

NEURL1B (N-17) - sc-243598 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NEURL1B (F-19) - sc-243599 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-NEURL1B antibody - ab156988 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab156988 stained U-87 MG cells. The cells were 100% methanol fixed for 5 minutes at -20°C and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1hour at room temperature to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab156988 at 5µg/ml) overnight at +4°C. The secondary antibody (pseudo-colored green) was Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) preadsorbed (ab150081) used at a 1/1000 dilution for 1hour at room temperature. Alexa Fluor® 594 WGA was used to label plasma membranes (pseudo-colored red) at a 1/200 dilution for 1hour at room temperature. DAPI was used to stain the cell nuclei (pseudo-colored blue) at a concentration of 1.43µM for 1hour at room temperature.

Anti-NEURL1B antibody - ab122400 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent staining of Human cell line U-251 MG shows positivity in vesicles. Recommended concentration of ab122400 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Anti-NEURL1B antibody - C-terminal - ab186686 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-NEURL1B antibody - C-terminal (ab186686) at 1 µg/ml + MCF7 whole cell lysate at 10 µg

Anti-NEURL1B Antibody (aa245-294) - LS-C206086 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NEURL1B antibody Western Blot of MCF7. Antibody dilution: 1 ug/ml.

Anti-NEURL1B Antibody (aa233-262, AP) - LS-C237982 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEURL1B Antibody (aa233-262, APC) - LS-C237983 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEURL1B Antibody (aa233-262, Biotin) - LS-C237985 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEURL1B Antibody (aa233-262, FITC) - LS-C237986 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEURL1B Antibody (aa233-262, PE) - LS-C237987 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEURL1B Antibody (aa233-262, Azide-free, HRP) - LS-C248901 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEURL1B Antibody (aa233-262) - LS-C323304 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

NEURL1B Antibody - NBP1-90499 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NEURL1B Antibody [NBP1-90499] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp

Anti-NEURL1B antibody produced in rabbit - HPA037612 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NEURL1B: <B>Cat. No. HPA037612</B>: Immunohistochemical staining of human rectum shows strong cytoplasmic positivity in glandular cells.

NEURL1B Antibody - C-terminal region (ARP72280_P050) - ARP72280_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NEURL1B antibody - orb221711 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

Anti-NEURL1B (aa 178-241) polyclonal antibody - DPABH-20701 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

NEURL1B antibody - TA330881 from Acris Antibodies

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Host: Rabbit; Target Name: NEURL1B; Sample Tissue: MCF7 Whole Cell lysates; Antibody Dilution: 1.0ug/ml

NEURL1B antibody (FITC) - orb222382 from Biorbyt

Prices $315.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

NEURL3 antibody - orb31274 from Biorbyt

Prices $187.00, $383.00
Sizes 80 μl (Trial size), 400 μl
Host Rabbit
Clonality Polyclonal
Western blot analysis of A549 cell line lysates (35ug/lane)using NEURL3 antibody (primary antibody dilution at: 1:1000)

ANTI-NEURL1B (N-TERM) antibody produced in rabbit - SAB1303030 from Sigma-Aldrich

Prices $336.50
Sizes 400 µl
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>NEURL1B (N-term): <B>Cat. No. SAB1303030</B>: NEURL1B in Human brain tissue with NEURL1B antibody (N-term) at 5 μg/mL.

Anti-NEURL1B Antibody A14794 - A14794 from Boster Bio

Prices $299.00
Sizes 1
Host Rabbit
Clonality Polyclonal

NEURL1B Antibody - C-terminal region : Biotin (ARP72280_P050-Biotin) - ARP72280_P050-Biotin from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

NEURL1B Antibody - C-terminal region : FITC (ARP72280_P050-FITC) - ARP72280_P050-FITC from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal
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