| Gene Symbol |
TBPL2
|
| Entrez Gene |
387332
|
| Alt Symbol |
TBP2, TRF3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
TATA box binding protein like 2
|
| Other Description |
TATA box-binding protein-like protein 2|TATA box-binding protein-related factor 3|TBP-like protein 2|TBP-related factor 3
|
| Swissprots |
Q17RU8 Q6SJ96
|
| Accessions |
EAW80675 EAW80676 Q6SJ96 AY457923 AAR24281 BC117159 AAI17160 BC117185 AAI17186 DQ448593 ABD93323 HQ258397 ADR83151 NM_199047 NP_950248
|
| Function |
Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity). {ECO:0000250|UniProtKB:Q6SJ95}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:14634207}. Nucleus {ECO:0000269|PubMed:14634207}. Note=Present in the cytoplasm during cytokenesis. {ECO:0000269|PubMed:14634207}.
|
| Tissue Specificity |
Ubiquitously expressed in all tissues examined with highest levels in heart, lung, ovary, spleen and testes. {ECO:0000269|PubMed:14634207, ECO:0000269|PubMed:17570761}.
|
| Top Pathways |
Huntington's disease, HTLV-I infection, Herpes simplex infection, Viral carcinogenesis, Epstein-Barr virus infection
|
![Western Blot: TBPL2 Overexpression Lysate (Adult Normal) [NBP2-04665] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TBPL2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8266_TBPL2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04665-img0001.jpg)