Gene Symbol | TBPL2 |
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Entrez Gene | 387332 |
Alt Symbol | TBP2, TRF3 |
Species | Human |
Gene Type | protein-coding |
Description | TATA box binding protein like 2 |
Other Description | TATA box-binding protein-like protein 2|TATA box-binding protein-related factor 3|TBP-like protein 2|TBP-related factor 3 |
Swissprots | Q17RU8 Q6SJ96 |
Accessions | EAW80675 EAW80676 Q6SJ96 AY457923 AAR24281 BC117159 AAI17160 BC117185 AAI17186 DQ448593 ABD93323 HQ258397 ADR83151 NM_199047 NP_950248 |
Function | Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity). {ECO:0000250|UniProtKB:Q6SJ95}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:14634207}. Nucleus {ECO:0000269|PubMed:14634207}. Note=Present in the cytoplasm during cytokenesis. {ECO:0000269|PubMed:14634207}. |
Tissue Specificity | Ubiquitously expressed in all tissues examined with highest levels in heart, lung, ovary, spleen and testes. {ECO:0000269|PubMed:14634207, ECO:0000269|PubMed:17570761}. |
Top Pathways | Huntington's disease, HTLV-I infection, Herpes simplex infection, Viral carcinogenesis, Epstein-Barr virus infection |
TBPL2 CRISPR/Cas9 KO Plasmid (h) - sc-415741 from Santa Cruz Biotechnology
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TBPL2 HDR Plasmid (h) - sc-415741-HDR from Santa Cruz Biotechnology
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TBPL2 Double Nickase Plasmid (h) - sc-415741-NIC from Santa Cruz Biotechnology
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TBPL2 Double Nickase Plasmid (h2) - sc-415741-NIC-2 from Santa Cruz Biotechnology
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TBPL2 CRISPR Activation Plasmid (h) - sc-415741-ACT from Santa Cruz Biotechnology
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TBPL2 CRISPR Activation Plasmid (h2) - sc-415741-ACT-2 from Santa Cruz Biotechnology
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TBPL2 Lentiviral Activation Particles (h) - sc-415741-LAC from Santa Cruz Biotechnology
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TBPL2 Lentiviral Activation Particles (h2) - sc-415741-LAC-2 from Santa Cruz Biotechnology
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TBPL2 siRNA (h) - sc-106603 from Santa Cruz Biotechnology
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TBPL2 shRNA Plasmid (h) - sc-106603-SH from Santa Cruz Biotechnology
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TBPL2 shRNA (h) Lentiviral Particles - sc-106603-V from Santa Cruz Biotechnology
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TBPL2 RNAi - H00387332-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN21099 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21099 from Sigma-Aldrich
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TBPL2 siRNA (Human) - CRJ7735 from Cohesion Biosciences
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TBPL2 - MBS8201082 from MyBioSource
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shRNA set against Human Tbpl2 (NM_199047.2) - SHH424288 from Creative biogene
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shRNA set against Human TBPL2(NM_199047.2) - SHL059390 from Creative biogene
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TBPL2 shRNA Plasmid (Human) - CHJ7735 from Cohesion Biosciences
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TBPL2 miRNA 3'UTR clone - MiUTR1H-10237 from Creative biogene
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