Gene Symbol | HMGB1 |
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Entrez Gene | 282691 |
Alt Symbol | - |
Species | Bovine |
Gene Type | protein-coding |
Description | high mobility group box 1 |
Other Description | HMG-1|high mobility group protein 1|high mobility group protein B1|high-mobility group box 1 |
Swissprots | Q3ZC39 A5D9G8 P10103 |
Accessions | DAA23902 P10103 BC102929 AAI02930 BT030587 ABQ13027 M26110 AAA30567 X12796 CAA31284 XM_005213558 XP_005213615 XM_010810664 XP_010808966 NM_176612 NP_788785 |
Function | DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267}. Chromosome {ECO:0000250}. |
Top Pathways | Base excision repair |
Native Bovine HMGB1 - HMGB1-8447B from Creative Biomart
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Recombinant Bovine High mobility group protein B1(HMGB1) - CSB-YP010553BO CSB-EP010553BO CSB-BP010553BO CSB-MP010553BO from Cusabio
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Native Bovine HMG1 - CSI13926 from Cell Science
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High mobility group protein B1 (HMGB1), Recombinant Protein - MBS962979 from MyBioSource
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