Gene Symbol |
GRPEL1
|
Entrez Gene |
80273
|
Alt Symbol |
HMGE
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
GrpE-like 1, mitochondrial (E. coli)
|
Other Description |
GrpE-like protein cochaperone|grpE protein homolog 1, mitochondrial|mt-GrpE#1
|
Swissprots |
Q549M6 Q9HAV7 B2R783
|
Accessions |
EAW82370 EAW82371 Q9HAV7 AF070525 AF087896 AAP97195 AF298592 AAG31605 AK098475 AK301695 BAG63167 AK312882 BAG35730 BC024242 AAH24242 DQ891523 ABM82449 DQ894713 ABM85639 NM_025196 NP_079472
|
Function |
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.
|
Subcellular Location |
Mitochondrion matrix.
|