Gene Symbol | GRPEL1 |
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Entrez Gene | 80273 |
Alt Symbol | HMGE |
Species | Human |
Gene Type | protein-coding |
Description | GrpE-like 1, mitochondrial (E. coli) |
Other Description | GrpE-like protein cochaperone|grpE protein homolog 1, mitochondrial|mt-GrpE#1 |
Swissprots | Q549M6 Q9HAV7 B2R783 |
Accessions | EAW82370 EAW82371 Q9HAV7 AF070525 AF087896 AAP97195 AF298592 AAG31605 AK098475 AK301695 BAG63167 AK312882 BAG35730 BC024242 AAH24242 DQ891523 ABM82449 DQ894713 ABM85639 NM_025196 NP_079472 |
Function | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. |
Subcellular Location | Mitochondrion matrix. |
GrpEL1 CRISPR/Cas9 KO Plasmid (h) - sc-413374 from Santa Cruz Biotechnology
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GrpEL1 HDR Plasmid (h) - sc-413374-HDR from Santa Cruz Biotechnology
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GrpEL1 Double Nickase Plasmid (h) - sc-413374-NIC from Santa Cruz Biotechnology
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GrpEL1 Double Nickase Plasmid (h2) - sc-413374-NIC-2 from Santa Cruz Biotechnology
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GrpEL1 CRISPR Activation Plasmid (h) - sc-413374-ACT from Santa Cruz Biotechnology
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GrpEL1 CRISPR Activation Plasmid (h2) - sc-413374-ACT-2 from Santa Cruz Biotechnology
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GrpEL1 Lentiviral Activation Particles (h) - sc-413374-LAC from Santa Cruz Biotechnology
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GrpEL1 Lentiviral Activation Particles (h2) - sc-413374-LAC-2 from Santa Cruz Biotechnology
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GrpEL1 siRNA (h) - sc-89323 from Santa Cruz Biotechnology
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GrpEL1 shRNA Plasmid (h) - sc-89323-SH from Santa Cruz Biotechnology
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GrpEL1 shRNA (h) Lentiviral Particles - sc-89323-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU006111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9709 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9709 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06925 from Sigma-Aldrich
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GRPEL1 siRNA (Human) - CRJ2834 from Cohesion Biosciences
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GRPEL1 - MBS8205290 from MyBioSource
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shRNA set against Human GRPE (NM_025196.2) - SHH308206 from Creative biogene
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shRNA set against Human GRPEL1(NM_025196.2) - SHH106121 from Creative biogene
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Human GRPEL1 siRNA - orb273335 from Biorbyt
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GRPEL1 shRNA Plasmid (Human) - CHJ2834 from Cohesion Biosciences
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GRPEL1 miRNA 3'UTR clone - MiUTR1H-04296 from Creative biogene
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