KLHL42

Gene Symbol KLHL42
Entrez Gene 57542
Alt Symbol Ctb9, KLHDC5
Species Human
Gene Type protein-coding
Description kelch-like family member 42
Other Description cullin-3-binding protein 9|kelch domain containing 5|kelch domain-containing protein 5|kelch-like family, member 42|kelch-like protein 42
Swissprots Q9P2K6 Q8N334 Q2VPK1
Accessions EAW96570 EAW96571 Q9P2K6 AA687307 AB037761 BAA92578 AK002197 AK095405 BAG53048 AL118635 AL702640 BC028742 AAH28742 BC108669 AAI08670 BC137116 AAI37117 BC137117 AAI37118 BQ218827 BX497104 CA771366 CD521625 EU446834 ABZ92363 T83155 XM_011520791 XP_011519093 XR_931314 XR_931315 NM_020782 NP_065833
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis. {ECO:0000269|PubMed:19261606}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:19261606}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:19261606}. Note=Predominantly in mitotic cells. Localized diffusely in the cytoplasm during the interphase. During metaphase is localized throughout the cell and more widely dispersed than the microtubules. In anaphase cells is localized between the two sets of separated chromosomes as well as at the spindle poles. During telophase is localized arround the nuclei of the two daughter cells. Not detected at the midbody region during cytokinesis.

KLHDC5 CRISPR/Cas9 KO Plasmid (h) - sc-410067 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KLHDC5 HDR Plasmid (h) - sc-410067-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KLHDC5 Double Nickase Plasmid (h) - sc-410067-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KLHDC5 Double Nickase Plasmid (h2) - sc-410067-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KLHDC5 CRISPR Activation Plasmid (h) - sc-410067-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KLHDC5 CRISPR Activation Plasmid (h2) - sc-410067-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KLHDC5 Lentiviral Activation Particles (h) - sc-410067-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KLHDC5 Lentiviral Activation Particles (h2) - sc-410067-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KLHDC5 siRNA (h) - sc-95696 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KLHDC5 shRNA Plasmid (h) - sc-95696-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KLHDC5 shRNA (h) Lentiviral Particles - sc-95696-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU013571 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11263 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11263 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

KLHL42 siRNA (Human) - CRJ1523 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human KLHDC5 (NM_020782.1) - SHH325959 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human KLHDC5(NM_020782.1) - SHL200574 from Creative biogene

Category siRNA
Species Reactivities Human

KLHL42 shRNA Plasmid (Human) - CHJ1523 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KLHDC5 miRNA 3'UTR clone - MiUTR1H-05363 from Creative biogene

Species Reactivities Human
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