| Gene Symbol | Cxcr3 |
|---|---|
| Entrez Gene | 84475 |
| Alt Symbol | Gpr9 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | chemokine (C-X-C motif) receptor 3 |
| Other Description | C-X-C chemokine receptor type 3|CXC-R3|CXCR-3|G protein-coupled receptor 9|IP-10 receptor|interferon-inducible protein 10 receptor |
| Swissprots | Q9JII9 |
| Accessions | EDL95884 Q9JII9 AF223642 AAF76982 BC091136 AAH91136 NM_053415 NP_445867 |
| Function | Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response (By similarity). {ECO:0000250}. |
| Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |