| Gene Symbol |
Cxcr3
|
| Entrez Gene |
84475
|
| Alt Symbol |
Gpr9
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
chemokine (C-X-C motif) receptor 3
|
| Other Description |
C-X-C chemokine receptor type 3|CXC-R3|CXCR-3|G protein-coupled receptor 9|IP-10 receptor|interferon-inducible protein 10 receptor
|
| Swissprots |
Q9JII9
|
| Accessions |
EDL95884 Q9JII9 AF223642 AAF76982 BC091136 AAH91136 NM_053415 NP_445867
|
| Function |
Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Chemokine signaling pathway
|