Gene Symbol | Cxcr3 |
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Entrez Gene | 84475 |
Alt Symbol | Gpr9 |
Species | Rat |
Gene Type | protein-coding |
Description | chemokine (C-X-C motif) receptor 3 |
Other Description | C-X-C chemokine receptor type 3|CXC-R3|CXCR-3|G protein-coupled receptor 9|IP-10 receptor|interferon-inducible protein 10 receptor |
Swissprots | Q9JII9 |
Accessions | EDL95884 Q9JII9 AF223642 AAF76982 BC091136 AAH91136 NM_053415 NP_445867 |
Function | Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
CompoZr® Knockout ZFN Kit - CKOZFN52642 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND52642 from Sigma-Aldrich
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CXCR3 siRNA (Rat) - CRR2602 from Cohesion Biosciences
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CXCR3 - MBS8239574 from MyBioSource
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shRNA set against Rat CXCR3 (NM_053415.1) - SHH272285 from Creative biogene
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shRNA set against Rat Cxcr3(NM_053415.1) - SHG212969 from Creative biogene
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Rat CXCR3 siRNA - orb297451 from Biorbyt
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CXCR3 shRNA Plasmid (Rat) - CHR2602 from Cohesion Biosciences
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CXCR3 miRNA 3'UTR clone - MiUTR1R-01295 from Creative biogene
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