| Gene Symbol |
UPK3B
|
| Entrez Gene |
80761
|
| Alt Symbol |
P35, UP3B, UPIIIB
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
uroplakin 3B
|
| Other Description |
uroplakin IIIb|uroplakin-3b
|
| Swissprots |
A8MZA8 Q86W06 A8K231 Q75MM5 B3KPU5 A6NHH5 Q9BT76
|
| Accessions |
AAS07526 Q9BT76 AK056760 BAG51807 AK290096 BAF82785 AY233462 AAO89507 BC004304 AAH04304 BE615406 BM921749 BP352210 BQ689127 BU150542 HQ447843 ADQ32327 NM_030570 NP_085047 NM_182683 NP_872624 NM_182684 NP_872625
|
| Function |
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER). {ECO:0000269|PubMed:12446744}.
|