Gene Symbol | UPK3B |
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Entrez Gene | 80761 |
Alt Symbol | P35, UP3B, UPIIIB |
Species | Human |
Gene Type | protein-coding |
Description | uroplakin 3B |
Other Description | uroplakin IIIb|uroplakin-3b |
Swissprots | A8MZA8 Q86W06 A8K231 Q75MM5 B3KPU5 A6NHH5 Q9BT76 |
Accessions | AAS07526 Q9BT76 AK056760 BAG51807 AK290096 BAF82785 AY233462 AAO89507 BC004304 AAH04304 BE615406 BM921749 BP352210 BQ689127 BU150542 HQ447843 ADQ32327 NM_030570 NP_085047 NM_182683 NP_872624 NM_182684 NP_872625 |
Function | Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER). {ECO:0000269|PubMed:12446744}. |
UPIIIb CRISPR/Cas9 KO Plasmid (h) - sc-407617 from Santa Cruz Biotechnology
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UPIIIb HDR Plasmid (h) - sc-407617-HDR from Santa Cruz Biotechnology
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UPIIIb Double Nickase Plasmid (h) - sc-407617-NIC from Santa Cruz Biotechnology
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UPIIIb Double Nickase Plasmid (h2) - sc-407617-NIC-2 from Santa Cruz Biotechnology
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UPIIIb CRISPR Activation Plasmid (h) - sc-407617-ACT from Santa Cruz Biotechnology
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UPIIIb CRISPR Activation Plasmid (h2) - sc-407617-ACT-2 from Santa Cruz Biotechnology
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UPIIIb Lentiviral Activation Particles (h) - sc-407617-LAC from Santa Cruz Biotechnology
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UPIIIb Lentiviral Activation Particles (h2) - sc-407617-LAC-2 from Santa Cruz Biotechnology
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UPIIIb siRNA (h) - sc-89371 from Santa Cruz Biotechnology
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UPIIIb shRNA Plasmid (h) - sc-89371-SH from Santa Cruz Biotechnology
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UPIIIb shRNA (h) Lentiviral Particles - sc-89371-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU142211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22524 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22524 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00871 from Sigma-Aldrich
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UPK3B siRNA (Human) - CRJ2904 from Cohesion Biosciences
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UPK3B - MBS8231664 from MyBioSource
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shRNA set against Human UPK3B (NM_182684.1) - SHH440824 from Creative biogene
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shRNA set against Human UPK3B(NM_182684.1) - SHL115694 from Creative biogene
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shRNA set against Human UPK3B(NM_030570.2) - SHL115776 from Creative biogene
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shRNA set against Human UPK3B(NM_182684.1) - SHL115822 from Creative biogene
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Human UPK3B siRNA - orb273405 from Biorbyt
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UPK3B shRNA Plasmid (Human) - CHJ2904 from Cohesion Biosciences
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UPK3B miRNA 3'UTR clone - MiUTR1H-11028 from Creative biogene
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UPK3B miRNA 3'UTR clone - MiUTR1H-11029 from Creative biogene
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