Gene Symbol |
PLCD1
|
Entrez Gene |
5333
|
Alt Symbol |
NDNC3, PLC-III
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
phospholipase C, delta 1
|
Other Description |
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1|PLC-delta-1|phosphoinositide phospholipase C-delta-1|phospholipase C-III
|
Swissprots |
Q86VN8 B3KR14 P51178
|
Accessions |
EAW64507 P51178 AB209862 BAD93099 AK090774 BAG52226 AK098690 AK127813 BAG54577 AK292324 BAF85013 BC050382 AAH50382 BX647927 CAI46087 CX164303 DA017409 DA083758 U09117 AAA73567 NM_001130964 NP_001124436 NM_006225 NP_006216 NR_024071
|
Function |
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Essential for trophoblast and placental development.
|
Top Pathways |
Calcium signaling pathway, Inositol phosphate metabolism, Phosphatidylinositol signaling system
|