Gene Symbol | PLCD1 |
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Entrez Gene | 5333 |
Alt Symbol | NDNC3, PLC-III |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase C, delta 1 |
Other Description | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1|PLC-delta-1|phosphoinositide phospholipase C-delta-1|phospholipase C-III |
Swissprots | Q86VN8 B3KR14 P51178 |
Accessions | EAW64507 P51178 AB209862 BAD93099 AK090774 BAG52226 AK098690 AK127813 BAG54577 AK292324 BAF85013 BC050382 AAH50382 BX647927 CAI46087 CX164303 DA017409 DA083758 U09117 AAA73567 NM_001130964 NP_001124436 NM_006225 NP_006216 NR_024071 |
Function | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Essential for trophoblast and placental development. |
Top Pathways | Calcium signaling pathway, Inositol phosphate metabolism, Phosphatidylinositol signaling system |
PLC δ1 CRISPR/Cas9 KO Plasmid (h) - sc-402474 from Santa Cruz Biotechnology
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PLC δ1 HDR Plasmid (h) - sc-402474-HDR from Santa Cruz Biotechnology
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PLC δ1 Double Nickase Plasmid (h) - sc-402474-NIC from Santa Cruz Biotechnology
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PLC δ1 Double Nickase Plasmid (h2) - sc-402474-NIC-2 from Santa Cruz Biotechnology
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PLC δ1 CRISPR Activation Plasmid (h) - sc-402474-ACT from Santa Cruz Biotechnology
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PLC δ1 CRISPR Activation Plasmid (h2) - sc-402474-ACT-2 from Santa Cruz Biotechnology
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PLC δ1 Lentiviral Activation Particles (h) - sc-402474-LAC from Santa Cruz Biotechnology
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PLC δ1 Lentiviral Activation Particles (h2) - sc-402474-LAC-2 from Santa Cruz Biotechnology
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PLC δ1 siRNA (h) - sc-40841 from Santa Cruz Biotechnology
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PLC δ1 shRNA Plasmid (h) - sc-40841-SH from Santa Cruz Biotechnology
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PLC δ1 shRNA (h) Lentiviral Particles - sc-40841-V from Santa Cruz Biotechnology
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PLC δ siRNA (h) - sc-40843 from Santa Cruz Biotechnology
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PLC δ shRNA Plasmid (h) - sc-40843-SH from Santa Cruz Biotechnology
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PLC δ shRNA (h) Lentiviral Particles - sc-40843-V from Santa Cruz Biotechnology
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Phospholipase C delta 1 RNAi - H00005333-R01 from Novus Biologicals
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MISSION® esiRNA - EHU145211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16924 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16924 from Sigma-Aldrich
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PLCD1 siRNA (Human) - CRH3573 from Cohesion Biosciences
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PLC δ1 CRISPR/Cas9 KO Plasmid (h2) - sc-402474-KO-2 from Santa Cruz Biotechnology
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PLC δ1 HDR Plasmid (h2) - sc-402474-HDR-2 from Santa Cruz Biotechnology
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Human PLCD1 siRNA - orb264075 from Biorbyt
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PLCD1 shRNA Plasmid (Human) - CHH3573 from Cohesion Biosciences
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