| Gene Symbol | CXCL2 |
|---|---|
| Entrez Gene | 2920 |
| Alt Symbol | CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | chemokine (C-X-C motif) ligand 2 |
| Other Description | C-X-C motif chemokine 2|GRO2 oncogene|MGSA beta|MIP2-alpha|gro-beta|growth-regulated protein beta|macrophage inflammatory protein 2-alpha|melanoma growth stimulatory activity beta |
| Swissprots | P19875 Q6FGD6 Q9UPB8 |
| Accessions | AAA03453 AAP13104 EAX05700 EAX05701 P19875 AF043340 AAC03540 AK308504 BC015753 AAH15753 BC053653 BX334969 CR542171 CAG46968 M36820 AAA63183 M57731 AAA63182 X53799 CAA37808 NM_002089 NP_002080 |
| Function | Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. {ECO:0000269|PubMed:10725737}. |
| Subcellular Location | Secreted. |
| Top Pathways | Cytokine-cytokine receptor interaction, NOD-like receptor signaling pathway, Chemokine signaling pathway, Salmonella infection, Legionellosis |