| Gene Symbol |
CXCL2
|
| Entrez Gene |
2920
|
| Alt Symbol |
CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chemokine (C-X-C motif) ligand 2
|
| Other Description |
C-X-C motif chemokine 2|GRO2 oncogene|MGSA beta|MIP2-alpha|gro-beta|growth-regulated protein beta|macrophage inflammatory protein 2-alpha|melanoma growth stimulatory activity beta
|
| Swissprots |
P19875 Q6FGD6 Q9UPB8
|
| Accessions |
AAA03453 AAP13104 EAX05700 EAX05701 P19875 AF043340 AAC03540 AK308504 BC015753 AAH15753 BC053653 BX334969 CR542171 CAG46968 M36820 AAA63183 M57731 AAA63182 X53799 CAA37808 NM_002089 NP_002080
|
| Function |
Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. {ECO:0000269|PubMed:10725737}.
|
| Subcellular Location |
Secreted.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, NOD-like receptor signaling pathway, Chemokine signaling pathway, Salmonella infection, Legionellosis
|
![Western Blot: GRO2 Overexpression Lysate (Adult Normal) [NBL1-09627] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GRO2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9157_GRO2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09627-img0002.jpg)