Gene Symbol |
TCEA2
|
Entrez Gene |
6919
|
Alt Symbol |
TFIIS
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
transcription elongation factor A (SII), 2
|
Other Description |
testis-specific S-II|transcription elongation factor A protein 2|transcription elongation factor S-II protein 2|transcription elongation factor TFIIS.1|transcription elongation factor TFIIS.l
|
Swissprots |
Q8TD38 B3KNM1 Q15560 Q8TD37
|
Accessions |
AAC39553 EAW75168 EAW75169 EAW75170 Q15560 AJ844626 AJ844627 CAH59746 AK027824 BAG51383 AK226140 AW474513 BC014211 BC018896 AAH18896 BC031877 BC050623 AAH50623 BC050624 BC056407 BC098585 BI668232 BI756937 CB961240 CR456940 CAG33221 D50495 BAA09089 EU446904 ABZ92433 HG511555 XM_005260229 XP_005260286 XM_011529022 XP_011527324 XM_011529023 XP_011527325 XM_011529024 XP_011527326 XM_011529025 XP_011527327 XM_011529026 XP_011527328 XM_011529027 XP_011527329 NM_003195 NP_003186 NM_198723 NP_942016
|
Function |
Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. {ECO:0000269|PubMed:12034815}.
|
Subcellular Location |
Nucleus.
|
Tissue Specificity |
Testis and ovary specific. {ECO:0000269|PubMed:8566795}.
|