Gene Symbol | LYPLA2 |
---|---|
Entrez Gene | 11313 |
Alt Symbol | APT-2, APT2, DJ886K2.4 |
Species | Human |
Gene Type | protein-coding |
Description | lysophospholipase II |
Other Description | LPL-II|acyl-protein thioesterase 2|lysoPLA II |
Swissprots | Q7Z4Z2 O95372 |
Accessions | EAW95077 EAW95078 EAW95079 EAW95080 EAW95081 EAW95082 O95372 AF090423 AAP97210 AF098668 AAC72844 AK024724 BC017034 AAH17034 BC017193 AAH17193 DQ896824 ABM87823 EU176281 ABW03732 XM_005245728 XP_005245785 NM_007260 NP_009191 |
Function | May hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has lysophospholipase activity (By similarity). Deacylates GAP43. {ECO:0000250, ECO:0000269|PubMed:21152083}. |
Subcellular Location | Cytoplasm {ECO:0000305}. |
Top Pathways | Glycerophospholipid metabolism |