Gene Symbol | LYPLA2 |
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Entrez Gene | 11313 |
Alt Symbol | APT-2, APT2, DJ886K2.4 |
Species | Human |
Gene Type | protein-coding |
Description | lysophospholipase II |
Other Description | LPL-II|acyl-protein thioesterase 2|lysoPLA II |
Swissprots | Q7Z4Z2 O95372 |
Accessions | EAW95077 EAW95078 EAW95079 EAW95080 EAW95081 EAW95082 O95372 AF090423 AAP97210 AF098668 AAC72844 AK024724 BC017034 AAH17034 BC017193 AAH17193 DQ896824 ABM87823 EU176281 ABW03732 XM_005245728 XP_005245785 NM_007260 NP_009191 |
Function | May hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has lysophospholipase activity (By similarity). Deacylates GAP43. {ECO:0000250, ECO:0000269|PubMed:21152083}. |
Subcellular Location | Cytoplasm {ECO:0000305}. |
Top Pathways | Glycerophospholipid metabolism |
LYPLA2 CRISPR/Cas9 KO Plasmid (h) - sc-405133 from Santa Cruz Biotechnology
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LYPLA2 HDR Plasmid (h) - sc-405133-HDR from Santa Cruz Biotechnology
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LYPLA2 Double Nickase Plasmid (h) - sc-405133-NIC from Santa Cruz Biotechnology
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LYPLA2 Double Nickase Plasmid (h2) - sc-405133-NIC-2 from Santa Cruz Biotechnology
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LYPLA2 CRISPR Activation Plasmid (h) - sc-405133-ACT from Santa Cruz Biotechnology
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LYPLA2 CRISPR Activation Plasmid (h2) - sc-405133-ACT-2 from Santa Cruz Biotechnology
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LYPLA2 Lentiviral Activation Particles (h) - sc-405133-LAC from Santa Cruz Biotechnology
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LYPLA2 Lentiviral Activation Particles (h2) - sc-405133-LAC-2 from Santa Cruz Biotechnology
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LYPLA2 siRNA (h) - sc-78672 from Santa Cruz Biotechnology
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LYPLA2 shRNA Plasmid (h) - sc-78672-SH from Santa Cruz Biotechnology
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LYPLA2 shRNA (h) Lentiviral Particles - sc-78672-V from Santa Cruz Biotechnology
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LYPLA2 RNAi - H00011313-R01 from Novus Biologicals
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MISSION® esiRNA - EHU108611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12862 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12862 from Sigma-Aldrich
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LYPLA2 siRNA (Human) - CRH7743 from Cohesion Biosciences
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shRNA set against Human LYPLA2 (NM_007260.2) - SHH336111 from Creative biogene
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shRNA set against Human LYPLA2(NM_007260.2) - SHH168581 from Creative biogene
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Human LYPLA2 siRNA - orb268245 from Biorbyt
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LYPLA2 shRNA Plasmid (Human) - CHH7743 from Cohesion Biosciences
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LYPLA2 miRNA 3'UTR clone - MiUTR1H-05977 from Creative biogene
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