Gene Symbol |
St6galnac1
|
Entrez Gene |
20445
|
Alt Symbol |
Siat7a
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
|
Other Description |
SIAT7-A|ST6GalNAc I|ST6GalNAcI|alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1|sialyltransferase 7 ((alpha-N-acetylneuraminyl 2,3-beta-galactosyl-1,3)-N-acetyl galactosaminde alpha-2,6-sialyltransferase) A|sialyltransferase 7A
|
Swissprots |
Q9JJP5 A2AA23 Q9QZ39
|
Accessions |
CAA71341 CAC10558 Q9QZ39 AK155119 BC141095 AAI41096 BC145373 AAI45374 BC145374 AAI45375 BE847090 Y11274 CAA72137 NM_011371 NP_035501
|
Function |
Transfers CMP-NeuAc with an alpha-2,6-linkage to the GalNAc residues of GalNAc-O-Ser/Thr, Gal-beta-1,3-GalNAc-O-Ser/Thr and NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-O-Ser/Thr are substrates. Higher activity towards GalNAc-O-Ser/Thr. {ECO:0000269|PubMed:10788794}.
|
Subcellular Location |
Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
Tissue Specificity |
Submaxillary gland, mammary gland, spleen and colon.
|
Top Pathways |
Mucin type O-Glycan biosynthesis
|