Gene Symbol | St6galnac1 |
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Entrez Gene | 20445 |
Alt Symbol | Siat7a |
Species | Mouse |
Gene Type | protein-coding |
Description | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 |
Other Description | SIAT7-A|ST6GalNAc I|ST6GalNAcI|alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1|sialyltransferase 7 ((alpha-N-acetylneuraminyl 2,3-beta-galactosyl-1,3)-N-acetyl galactosaminde alpha-2,6-sialyltransferase) A|sialyltransferase 7A |
Swissprots | Q9JJP5 A2AA23 Q9QZ39 |
Accessions | CAA71341 CAC10558 Q9QZ39 AK155119 BC141095 AAI41096 BC145373 AAI45374 BC145374 AAI45375 BE847090 Y11274 CAA72137 NM_011371 NP_035501 |
Function | Transfers CMP-NeuAc with an alpha-2,6-linkage to the GalNAc residues of GalNAc-O-Ser/Thr, Gal-beta-1,3-GalNAc-O-Ser/Thr and NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-O-Ser/Thr are substrates. Higher activity towards GalNAc-O-Ser/Thr. {ECO:0000269|PubMed:10788794}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Submaxillary gland, mammary gland, spleen and colon. |
Top Pathways | Mucin type O-Glycan biosynthesis |
Sialyltransferase 7A CRISPR/Cas9 KO Plasmid (m) - sc-422938 from Santa Cruz Biotechnology
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Sialyltransferase 7A HDR Plasmid (m) - sc-422938-HDR from Santa Cruz Biotechnology
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Sialyltransferase 7A Double Nickase Plasmid (m) - sc-422938-NIC from Santa Cruz Biotechnology
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Sialyltransferase 7A Double Nickase Plasmid (m2) - sc-422938-NIC-2 from Santa Cruz Biotechnology
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Sialyltransferase 7A CRISPR Activation Plasmid (m) - sc-422938-ACT from Santa Cruz Biotechnology
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Sialyltransferase 7A CRISPR Activation Plasmid (m2) - sc-422938-ACT-2 from Santa Cruz Biotechnology
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Sialyltransferase 7A Lentiviral Activation Particles (m) - sc-422938-LAC from Santa Cruz Biotechnology
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Sialyltransferase 7A Lentiviral Activation Particles (m2) - sc-422938-LAC-2 from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN42125 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND42125 from Sigma-Aldrich
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ST6GALNAC1 siRNA (Mouse) - CRM3720 from Cohesion Biosciences
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ST6GALNAC1 - MBS8200395 from MyBioSource
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shRNA set against Mouse ST6GALNAC1 (NM_011371.2) - SHH418912 from Creative biogene
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shRNA set against Mouse St6galnac1(NM_011371.2) - SHL038460 from Creative biogene
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Mouse ST6GALNAC1 siRNA - orb283196 from Biorbyt
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ST6GALNAC1 shRNA Plasmid (Mouse) - CHM3720 from Cohesion Biosciences
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ST6GALNAC1 miRNA 3'UTR clone - MiUTR1M-11279 from Creative biogene
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