| Gene Symbol |
FCRL1
|
| Entrez Gene |
115350
|
| Alt Symbol |
CD307a, FCRH1, IFGP1, IRTA5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Fc receptor-like 1
|
| Other Description |
Fc receptor-like protein 1|IFGP family protein 1|fc receptor homolog 1|fcR-like protein 1|hIFGP1|immune receptor translocation-associated protein 5|immunoglobulin superfamily Fc receptor, gp42
|
| Swissprots |
Q96PJ6 B2RE05 Q8NDI0 Q8N759 Q96LA6
|
| Accessions |
ABK41917 EAW52860 EAW52861 EAW52862 EAW52863 Q96LA6 AF329488 AAL23898 AF459634 AAL60250 AK096690 BAC04842 AK315748 BAG38102 AL833674 AL833970 CAD38815 AY043464 AAK91777 BC021274 BC033690 AAH33690 DA939902 HQ447331 ADQ31817 XM_005244866 XP_005244923 XM_005244867 XP_005244924 XM_005244869 XP_005244926 XM_011509125 XP_011507427 XM_011509126 XP_011507428 XM_011509127 XP_011507429 XM_011509128 XP_011507430 XM_011509129 XP_011507431 XM_011509130 XP_011507432 XM_011509131 XP_011507433 XM_011509132 XP_011507434 XM_011509133 XP_011507435 XM_011509134 XP_011507436 XM_011509135 XP_011507437 XM_011509136 XP_011507438 XM_011509137 XP_011507439 XR_921738 XR_921739 XR_921740 NM_001159397 NP_001152869 NM_001159398 NP_001152870 NM_052938 NP_443170
|
| Function |
May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation. {ECO:0000269|PubMed:15479727}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:15479727, ECO:0000269|PubMed:16849395}; Single-pass type I membrane protein {ECO:0000269|PubMed:15479727, ECO:0000269|PubMed:16849395}.
|
| Tissue Specificity |
Primarily expressed in secondary lymphoid tissues by mature subsets of B-cells. Detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. Specifically expressed by mature B lineage cells with higher expression in naive versus memory B-cells (at protein level). {ECO:0000269|PubMed:11493702, ECO:0000269|PubMed:11929751, ECO:0000269|PubMed:15479727, ECO:0000269|PubMed:16849395}.
|
