Gene Symbol | FCRL1 |
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Entrez Gene | 115350 |
Alt Symbol | CD307a, FCRH1, IFGP1, IRTA5 |
Species | Human |
Gene Type | protein-coding |
Description | Fc receptor-like 1 |
Other Description | Fc receptor-like protein 1|IFGP family protein 1|fc receptor homolog 1|fcR-like protein 1|hIFGP1|immune receptor translocation-associated protein 5|immunoglobulin superfamily Fc receptor, gp42 |
Swissprots | Q96PJ6 B2RE05 Q8NDI0 Q8N759 Q96LA6 |
Accessions | ABK41917 EAW52860 EAW52861 EAW52862 EAW52863 Q96LA6 AF329488 AAL23898 AF459634 AAL60250 AK096690 BAC04842 AK315748 BAG38102 AL833674 AL833970 CAD38815 AY043464 AAK91777 BC021274 BC033690 AAH33690 DA939902 HQ447331 ADQ31817 XM_005244866 XP_005244923 XM_005244867 XP_005244924 XM_005244869 XP_005244926 XM_011509125 XP_011507427 XM_011509126 XP_011507428 XM_011509127 XP_011507429 XM_011509128 XP_011507430 XM_011509129 XP_011507431 XM_011509130 XP_011507432 XM_011509131 XP_011507433 XM_011509132 XP_011507434 XM_011509133 XP_011507435 XM_011509134 XP_011507436 XM_011509135 XP_011507437 XM_011509136 XP_011507438 XM_011509137 XP_011507439 XR_921738 XR_921739 XR_921740 NM_001159397 NP_001152869 NM_001159398 NP_001152870 NM_052938 NP_443170 |
Function | May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation. {ECO:0000269|PubMed:15479727}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:15479727, ECO:0000269|PubMed:16849395}; Single-pass type I membrane protein {ECO:0000269|PubMed:15479727, ECO:0000269|PubMed:16849395}. |
Tissue Specificity | Primarily expressed in secondary lymphoid tissues by mature subsets of B-cells. Detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. Specifically expressed by mature B lineage cells with higher expression in naive versus memory B-cells (at protein level). {ECO:0000269|PubMed:11493702, ECO:0000269|PubMed:11929751, ECO:0000269|PubMed:15479727, ECO:0000269|PubMed:16849395}. |
FcRH1 CRISPR/Cas9 KO Plasmid (h) - sc-416489 from Santa Cruz Biotechnology
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FcRH1 HDR Plasmid (h) - sc-416489-HDR from Santa Cruz Biotechnology
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FcRH1 Double Nickase Plasmid (h) - sc-416489-NIC from Santa Cruz Biotechnology
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FcRH1 Double Nickase Plasmid (h2) - sc-416489-NIC-2 from Santa Cruz Biotechnology
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FcRH1 CRISPR Activation Plasmid (h) - sc-416489-ACT from Santa Cruz Biotechnology
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FcRH1 CRISPR Activation Plasmid (h2) - sc-416489-ACT-2 from Santa Cruz Biotechnology
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FcRH1 Lentiviral Activation Particles (h) - sc-416489-LAC from Santa Cruz Biotechnology
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FcRH1 Lentiviral Activation Particles (h2) - sc-416489-LAC-2 from Santa Cruz Biotechnology
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FcRH1 siRNA (h) - sc-45628 from Santa Cruz Biotechnology
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FcRH1 shRNA Plasmid (h) - sc-45628-SH from Santa Cruz Biotechnology
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FcRH1 shRNA (h) Lentiviral Particles - sc-45628-V from Santa Cruz Biotechnology
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FCRL1/FcRH1 RNAi - H00115350-R02 from Novus Biologicals
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MISSION® esiRNA - EHU157701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8601 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8601 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09111 from Sigma-Aldrich
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FCRL1 siRNA (Human) - CRJ4442 from Cohesion Biosciences
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FCRL1 - MBS8214486 from MyBioSource
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shRNA set against Human FCRL1 (NM_052938.4) - SHH293849 from Creative biogene
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Human FCRL1 siRNA - orb274943 from Biorbyt
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FCRL1 shRNA Plasmid (Human) - CHJ4442 from Cohesion Biosciences
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FCRL1 miRNA 3'UTR clone - MiUTR4H-TG03505 from Creative biogene
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